Clin Gastroenterology H:内镜超声成像可以鉴别腹腔淋巴结中乳糜神经节

2019-01-11 MedSci MedSci原创

内镜超声(EUS)可以让腹腔淋巴结(CLN)和腹腔神经节(CG)的显示可视化。在临床工作中区分这些结构对于肿瘤分期和CG消融治疗是十分重要的。因此,本项研究的目的是使用严格的细胞病理学参考标准评估EUS在区分CLN和CG方面的准确性

背景与目的
内镜超声(EUS)可以让腹腔淋巴结(CLN)和腹腔神经节(CG)的显示可视化。在临床工作中区分这些结构对于肿瘤分期和CG消融治疗是十分重要的。因此,本项研究的目的是使用严格的细胞病理学参考标准评估EUS在区分CLN和CG方面的准确性。

方法
研究人员从EUS和细胞病理学数据库中收集了从2004年10月1日到2017年3月1日间接受超声内镜成像患者临床资料并对这些结果与细胞学的结果进行了比较。将EUS成像(即指数测试)结果与参考标准的结果进行比较。一位放射科医师重新审查了来自94个随机选择的参考标准患者的100个病灶的计算机断层扫描和磁共振图像,以确定CLN和CG检测的比率。

结果
共有504名患者(平均年龄63.4±13.2岁; 292名男性)接受了7次EUS检测,总共有566个病灶被认为是CLN或CG; 细胞学参考标准可用于521个病灶(92.1%)。当我们排除不确定的细胞学结果时,EUS准确地鉴定了281/286个CLN(98.3%)和166/186个CG(89.2%),总体准确度为447/472(94.7%)。EUS区分CG与CLNs的敏感性为93.3%,特异性为93.7%,阳性预测值为96.2%,阴性预测值为89.2%。

结论
EUS可以准确地将CLN与CG区分开来。因此,EUS可用于提高肿瘤分期的准确性,选择适合肿瘤阶段的治疗,以及指导CG消融治疗。

原始出处:

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    2019-12-06 许安
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    2019-01-13 sodoo
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