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NEJM：软骨母细胞型骨肉瘤肺转移-病例报道

2018-04-12 xing.T MedSci原创

软骨母细胞骨肉瘤肺转移
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一周后，病人出现呼吸急促、左侧胸膜炎性胸痛。患者呼吸周围空气时血氧饱和度为94%。胸部摄影显示肺部有无数病变（如图A所示）。胸部CT扫描证实双肺广泛存在，呈分叶状，部分钙化结节的肿块，提示为肺转移瘤（如图B所示）。

患者为一名21岁的女性，因右侧大腿进行性肿胀和疼痛8个月而到急诊就诊。

右下肢磁共振成像检查冠状面显示股骨膜环可见尺寸大小为30厘米，增强的肿块，以及右侧股静脉一个非闭塞性血栓，为此患者接受抗凝治疗。该股骨肿块活检证实诊断为软骨母细胞型骨肉瘤。



一周后，病人出现呼吸急促、左侧胸膜炎性胸痛。患者呼吸周围空气时血氧饱和度为94%。胸部摄影显示肺部有无数病变（如图A所示）。胸部CT扫描证实双肺广泛存在，呈分叶状，部分钙化结节的肿块，提示为肺转移瘤（如图B所示）。

该患者尽管开始化疗，病情仍在好转。第二个化疗方案已经开始，并完成了五个周期，目前病情稳定。

原始出处：

Hirva Mamdani,et al. Pulmonary Metastases from Chondroblastic Osteosarcoma. N Engl J Med 2018; http://www.nejm.org/doi/full/10.1056/NEJMicm1711874

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    2018-04-13 licz0428

    #肺转移#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1555522, encodeId=c629155552294, content=<a href='/topic/show?id=6d4f8232623' target=_blank style='color:#2F92EE;'>#肺转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82326, encryptionId=6d4f8232623, topicName=肺转移)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9b6914619384, createdName=licz0428, createdTime=Fri Apr 13 21:44:00 CST 2018, time=2018-04-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=305055, encodeId=033d30505520, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Thu Apr 12 08:34:55 CST 2018, time=2018-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=305048, encodeId=41ae30504815, content=好知识值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59321624668, createdName=zb1235672, createdTime=Thu Apr 12 07:46:04 CST 2018, time=2018-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=305032, encodeId=9d9330503213, content=了解了解.学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Thu Apr 12 07:22:11 CST 2018, time=2018-04-12, status=1, ipAttribution=)]
    2018-04-12 明月清辉

    谢谢分享.学习了

    0

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    2018-04-12 zb1235672

    好知识值得学习

    0

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    2018-04-12 1dd8c52fm63(暂无匿称)

    了解了解.学习学习

    0