J Microbiol Immunol Infect:早发性湿疹与牛奶过敏、鼻炎和哮喘风险的增加相关

2019-06-11 AlexYang MedSci原创

过敏性湿疹和食物过敏经常在儿童早期发生。然而,湿疹起始与过敏原敏感有关的特应性疾病的发生的相关性的关系仍旧不清楚。最近,有研究人员跟踪调查了186名儿童,跟踪调查为期4年。研究人员将儿童分成3个小组:早发性湿疹组(小于2岁,n=55),晚发性湿疹组(不小于2岁,n=40)和不具有湿疹组(n=91)。研究发现,在具有早发性湿疹组中,食物过敏,尤其是牛奶过敏患病率与1、1.5、2、3和4岁的没有湿疹的

过敏性湿疹和食物过敏经常在儿童早期发生。然而,湿疹起始与过敏原敏感有关的特应性疾病的发生的相关性的关系仍旧不清楚。

最近,有研究人员跟踪调查了186名儿童,跟踪调查为期4年。研究人员将儿童分成3个小组:早发性湿疹组(小于2岁,n=55),晚发性湿疹组(不小于2岁,n=40)和不具有湿疹组(n=91)。研究发现,在具有早发性湿疹组中,食物过敏,尤其是牛奶过敏患病率与1、1.5、2、3和4岁的没有湿疹的参与者相比显著更高。更多的是,早发性湿疹或者晚发性湿疹组中1.5岁的患者的嗜酸性粒细胞数目显著更多。另外,早发性和晚发性湿疹与过敏性鼻炎更高的患病率在2、3和4岁时显著相关,在哮喘患者中为2岁。更多的是,早发性湿疹组的过敏性鼻炎(p=0.010)和哮喘(p=0.032)在4岁时风险显著增加。

最后,研究人员指出,早发性湿疹(小于2岁)儿童应该与儿童早期牛奶过敏患病率的增加和鼻炎哮喘风险的增加相关。

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    2019-08-16 xjy02
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    2019-10-19 sunylz
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Incyte制药公司近日宣布,III期TRuE-AD临床试验已经招募了第1名患者,以评估ruxolitinib作为青少年和成人患者(年龄≥12岁)单药治疗特应性皮炎(AD)的长期安全性和有效性。