Hypertension:再不减肥,小心高血压找上门!来自90万国人20年研究的提醒

2018-06-15 英硕 医学界心血管频道

这两天,我国学者又在《Hypertension》上发表了一篇文章,通过观察20年(1995~2014)来,超过90万超重和肥胖的儿童和青少年(年龄跨度为7~17岁)的血压水平,得出结论——超重和肥胖可增加此类人群高血压患病率!

这两天,我国学者又在《Hypertension》上发表了一篇文章,通过观察20年(1995~2014)来,超过90万超重和肥胖的儿童和青少年(年龄跨度为7~17岁)的血压水平,得出结论——超重和肥胖可增加此类人群高血压患病率!

什~么~,肥胖的魔爪竟然又伸向了祖国的花朵!既往研究已证实儿童高血压可进展为成人高血压,且前者是后者的最强预测因子。越来越多的证据表明,超重和肥胖可能是儿童高血压的病因。

可怜的孩子们,如果他们知道这些,会不会放下手中的鸡腿、可乐和汉堡。

但似乎实际情况并没有这么悲观。

很多国家(塞舌尔、韩国、日本、伊朗、美国等)发现尽管近些年孩子们的超重和肥胖率增加,但高血压的总体趋势却是下降的,比如塞舌尔研究发现肥胖儿童比例从1998年的5.5%增加至2006年的8.5%,但血压却下降了3 mmHg。我国尚缺少这方面的数据,于是Dong等学者对此进行了研究,提供了中国数据。

研究人员共纳入5个国家连续横断面调查的数据,共943128名学龄期儿童/青少年,年龄介于7~17岁。通过身体质量指数(BMI)定义超重和肥胖(图1),用水银血压表测量血压。经过研究后得出如下结果:


图1 各年龄段超重和肥胖临界值,超过临界值定义为超重或肥胖,比如2岁男孩,BMI超过18.41kg/m2为超重,超过20.09 kg/m2为肥胖

1.超重/肥胖患病率增加幅度超过高血压

表1 1995~2014年超重、肥胖和高血压患病率



高血压患病率最高见于2010年,最低见于2005年,收缩压自1995年至2005年平稳下降,随后至2014年逐渐上升。这种增幅趋势同样见于舒张压、男性、女性。


图2 1995~2014年7~17岁儿童/青少年高血压(HBP)、收缩期高血压(SHBP)、舒张期高血压(DHBP)、超重、肥胖患病率趋势图,A为男性,B为女性

2.血压水平和高血压患病率与BMI成正相关

研究将7~17岁儿童/青少年分为偏瘦、正常、超重和肥胖组,分别采集1995年、2000年、2005年、2010年和2014年这5年的收缩压、舒张压数值,根据图表发现1995~2014年血压水平和高血压患病率升高伴随BMI增加,尤其以超重组最为显着(图3、图4)。


图3 1995~2014年7~17岁儿童/青少年在不同BMI组SHBP和DHBP水平, A、C为男性,B、D为女性


图4 1995~2014年7~17岁儿童/青少年在不同BMI组HBP、SHBP和DHBP患病率, A、C、E为男性,B、D、F为女性

3.因超重/肥胖致高血压的归因危险度百分比增加

根据数据分析,1995~2014年7~17岁儿童/青少年因超重\肥胖致高血压的归因危险度百分比明显增加(表2,图5),不论男性、女性、收缩压还是舒张压。(说人话),也就是因为超重/肥胖引发高血压的人群在所有高血压人群中所占比重越来越大。

表2 1995~2014年7~17岁儿童/青少年因超重\肥胖致高血压的归因危险度百分比(%)




图5  1995~2014年7~17岁儿童/青少年因超重\肥胖致高血压的归因危险度百分比变化趋势,A为HBP,B为SHBP,C为DHBP

4.归因危险度百分比与高血压患病率增加幅度不一致

因超重\肥胖致高血压的归因危险度百分比随时间明显增加,但整体高血压患病率并未对应增加,可能与其他干预因素有关,如盐摄入量减少、高出生体重和缺乏体育锻炼等因素。儿童和青少年应减少盐摄入,多参加体育锻炼。

以前都以为什么“死肥宅”,什么“躺尸”特指成年人,原来连孩子都不能幸免,周末一定要带窝在家里,带着孩子到户外运动,吃健康食物,不仅有利于身体,增进了与孩子之间的感情,一举两得。

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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Fri Jun 15 08:42:15 CST 2018, time=2018-06-15, status=1, ipAttribution=)]
    2018-06-17 aa6081

    正努力减肥中.虽然不是很胖

    0

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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Fri Jun 15 08:42:15 CST 2018, time=2018-06-15, status=1, ipAttribution=)]
    2018-06-17 liuchuan1982

    超重和肥胖可增加此类人群高血压患病率!

    0

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    2018-06-15 漩涡尽头

    减肥减肥.祖国的花朵

    0

  7. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Fri Jun 15 08:42:15 CST 2018, time=2018-06-15, status=1, ipAttribution=)]
    2018-06-15 1201e5c5m39暂无昵称

    努力减肥

    0

  8. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Fri Jun 15 08:42:15 CST 2018, time=2018-06-15, status=1, ipAttribution=)]
    2018-06-15 wzb521zf

    一起学习学习

    0

  9. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Fri Jun 15 08:42:15 CST 2018, time=2018-06-15, status=1, ipAttribution=)]
    2018-06-15 深海的鱼

    正在积极控制

    0

  10. 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