J Clin Periodontol:光动力疗法在牙周治疗中的作用

2017-09-17 MedSci MedSci原创

为了评估光动力疗法(PDT)在慢性牙周炎的非手术治疗的的效果。

为了评估光动力疗法(PDT)在慢性牙周炎的非手术治疗的的效果。

材料和方法:采用随机,单盲,控制,平行分组的临床试验。 60例患者入选:20个健康对照和40名牙周炎患者。 40名患者被随机分入刮治和根面平整术(SRP)组或SRP + PDT组。记录包括:牙周状况(菌斑指数,探诊深度,临床退缩,临床附着水平,探诊出血和龈沟液体积,对应于381与428的关键位点),微生物(伴放线放线杆菌,牙龈卟啉单胞菌,福赛斯坦纳菌,齿垢密螺旋体,中间普氏菌和直肠弯曲菌,18与19个样本)和生化(白介素(IL)-1β,IL-6和肿瘤坏死因子(TNF)-α,核因子-κB配体(RANK-L)和骨保护素的受体活化剂(OPG)水平,18与19个样本)。

结果:在每一组中,临床参数有显着改善,但是组间没有显着差异。 与SRP组相比,SRP + PDT组的RANK-L在第13周显着下降。不仅仅是SRP,SRP + PDT组伴放线放线杆菌的丰度显着下降。

结论:中至晚度慢性牙周炎患者的治疗,与单纯SRP相比,辅助PDT除了伴放线放线杆菌量显着下降之外没有额外的改善

原始出处

Marta Segarra-Vidal, Sol Guerra-Ojeda, et al. Effects of photodynamic therapy in periodontal treatment: A randomized, controlled clinical trial. Journal of Clinical Periodontology. 2017 September. doi: 10.1111/jcpe.12768

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    2018-07-17 feather89
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    2017-09-25 三生有幸9135

    学习一下谢谢分享

    0

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    2017-09-18 zt123

    就是看男男

    0

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    2017-09-17 三生有幸9135

    学习一下谢谢分享

    0

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    2017-09-17 清风拂面

    很好的文章.谢谢分享

    0

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    2017-09-17 tanxingdoctor

    学习啦!谢谢分享!

    0

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