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OPKO和辉瑞宣布长效化生长激素GENOTROPIN治疗生长激素缺乏症儿童的3期临床成功

2019-10-21 不详 MedSci原创

OPKO辉瑞长效化生长激素GENOTROPIN生长激素缺乏症儿童3期临床成功
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OPKO Health和Pfizer宣布，其GENOTROPIN（生长激素）治疗儿童生长激素缺乏（GHD）症的somatrogon3期试验达到了非劣效性的主要终点。

OPKO Health和Pfizer宣布，其GENOTROPIN（生长激素）治疗儿童生长激素缺乏（GHD）症的somatrogon3期试验达到了非劣效性的主要终点。

该研究的主要结果表明，就治疗12个月时的身高而言，青春期前GHD的儿童每周一次服用生长激素治疗并不逊于每天一次服用生长激素（主要终点）。在研究中，对生长激素的耐受性一般良好，就治疗组之间观察到的不良事件的类型，数量和严重程度而言，与每天服用一次生长激素的剂量相当。

OPKO董事长兼首席执行官Phillip Frost医师表示："我们非常高兴地宣布这些令人欣慰的结果，证明了每周服用一次somatrogon在GHD患儿中的疗效。Somatrogon是一种结合了OPKO专有的长效技术的新分子实体。我们相信，与目前每天注射1剂的标准相比，Somatrogon代表了GHD儿童治疗方面的重大进步，可以提高患者对治疗的依从性和生活质量。"

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    2020-09-13 陆成振

    #OPKO#

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    2020-02-16 sunyl07

    #生长激素缺乏症儿童#

    0

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    2020-02-05 andy2087

    #3期临床#

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    2020-01-23 hukaixun

    #长效化生长激素#

    0

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    2019-10-23 lidong41

    #生长激素缺乏#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1759096, encodeId=eca31e590965d, content=<a href='/topic/show?id=c23c1342087' target=_blank style='color:#2F92EE;'>#OPKO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13420, encryptionId=c23c1342087, topicName=OPKO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5ce837418812, createdName=陆成振, createdTime=Sun Sep 13 15:56:00 CST 2020, time=2020-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798617, encodeId=976c1e98617c6, content=<a href='/topic/show?id=03386963456' target=_blank style='color:#2F92EE;'>#生长激素缺乏症儿童#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69634, encryptionId=03386963456, topicName=生长激素缺乏症儿童)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Sun Feb 16 00:56:00 CST 2020, time=2020-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1911244, encodeId=da101911244c7, content=<a href='/topic/show?id=18171289d6' target=_blank style='color:#2F92EE;'>#3期临床#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1289, encryptionId=18171289d6, topicName=3期临床)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d275294, createdName=andy2087, createdTime=Wed Feb 05 09:56:00 CST 2020, time=2020-02-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1743382, encodeId=31841e43382df, content=<a href='/topic/show?id=f1329693085' target=_blank style='color:#2F92EE;'>#长效化生长激素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96930, encryptionId=f1329693085, topicName=长效化生长激素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ff035117472, createdName=hukaixun, createdTime=Thu Jan 23 00:56:00 CST 2020, time=2020-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1407468, encodeId=de20140e4683c, content=<a href='/topic/show?id=a79569632f4' target=_blank style='color:#2F92EE;'>#生长激素缺乏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69632, encryptionId=a79569632f4, topicName=生长激素缺乏)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a3fa2654160, createdName=lidong41, createdTime=Wed Oct 23 12:56:00 CST 2019, time=2019-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631266, encodeId=ecc116312669c, content=<a href='/topic/show?id=0d2b1353679' target=_blank style='color:#2F92EE;'>#OTR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13536, encryptionId=0d2b1353679, topicName=OTR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fb2621702447, createdName=jichang, createdTime=Wed Oct 23 12:56:00 CST 2019, time=2019-10-23, status=1, ipAttribution=)]
    2019-10-23 jichang

    #OTR#

    0