Diabetes Care:研究揭示导致糖尿病持续存在而难以治愈的原因!

2018-01-13 sunshine2015 来宝网

根据1月9日在线发表在“糖尿病护理”上的研究,糖尿病和糖尿病前期的持续时间都与冠状动脉钙化斑块(CAC)和左心室功能障碍的存在独立相关。

新的免疫疗法增强身体摧毁癌细胞的能力】基于免疫系统可以被用来检测和杀死癌细胞的原理,很少有癌症治疗产生比免疫治疗药物更多的兴奋,这与在感染性微生物之后进行的方式非常相似。然而这些治疗仅对一些患者有益,并且在绝大多数情况下仍然无效。癌细胞很狡猾,他们有很多方法来保护自己免受冲击。

洛克菲勒团队现在正在报告一个战略,以避开癌症的保护性屏障,使免疫细胞更容易完成工作。这种方法专注于称为骨髓衍生抑制细胞或MDSC的免疫细胞,并且似乎能【糖尿病和前期糖尿病的持续存在与冠状动脉硬化斑块有关】根据1月9日在线发表在“糖尿病护理”上的研究,糖尿病和糖尿病前期的持续时间都与冠状动脉钙化斑块(CAC)和左心室功能障碍的存在独立相关。

来自马里兰州贝塞斯达的全国心脏,肺和血液研究所的Jared P. Reis博士及其同事检查了在成年早期的25年期间估计的糖尿病和前驱糖尿病的持续时间是否独立与CAC有关。数据包括3,628名18至30岁的白人和黑人,其基线(1985年至1986年)没有糖尿病或前驱糖尿病。

研究人员发现,12.7和53.8%的参与者分别患有糖尿病和前驱糖尿病,平均持续时间为10.7和9.5年。在调整社会人口学特征和其他心血管风险因素以及相互之间的相互调整之后,CAC存在的风险比分别是糖尿病和前驱糖尿病的每五年更长时间的1.15倍和1.07倍。糖尿病和前驱糖尿病持续时间与心脏收缩功能更差和早期舒张有关。糖尿病病程与舒张期充盈压较高也有相关性。

作者写道:“成年期糖尿病和前驱糖尿病的持续时间都与亚临床动脉粥样硬化和中年左心室收缩和舒张功能障碍独立相关。”

原始出处:

Jared P. Reis, Norrina B. Allen, Michael P. Bancks, et al. Duration of Diabetes and Prediabetes During Adulthood and Subclinical Atherosclerosis and Cardiac Dysfunction in Middle Age: The CARDIA Study. Diabetes Care 2018 Jan; dc172233. https://doi.org/10.2337/dc17-2233.

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    2018-01-18 sunsmile 2017

    很好

    0

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    2018-01-17 1e0f8808m18(暂无匿称)

    学习了.谢谢分享.

    0

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    2018-01-14 1e145228m78(暂无匿称)

    学习了.谢谢作者分享!

    0

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    2018-01-13 1e0e5a1fm42(暂无匿称)

    henhao

    0

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