赴美产子50天后竟现超大肝癌,中国医生如何助其与子同庆生

2018-09-03 屠俊 澎湃新闻

36岁产妇小米(化名),孕33周赴美国产子,回国后大约半个月,也就是产后50天竟然发现直径25公分的巨大肝癌且伴有梗阻性黄疸。要知道,一般肝肿瘤超过10公分就算巨大。本以为生命走到了尽头,但在中国医生的救治下,产妇接受超常规的介入,近日是手术成功一整年,小米各项指标均属正常,患者得以和自己的孩子同时庆生。令人疑惑的是,产妇为何在整个孕期都没有检查出肝脏肿瘤?在美国产子是近年来不少中产家庭会考虑的问

36岁产妇小米(化名),孕33周赴美国产子,回国后大约半个月,也就是产后50天竟然发现直径25公分的巨大肝癌且伴有梗阻性黄疸。要知道,一般肝肿瘤超过10公分就算巨大。

本以为生命走到了尽头,但在中国医生的救治下,产妇接受超常规的介入,近日是手术成功一整年,小米各项指标均属正常,患者得以和自己的孩子同时庆生。

令人疑惑的是,产妇为何在整个孕期都没有检查出肝脏肿瘤?在美国产子是近年来不少中产家庭会考虑的问题,市场上也催生出很多赴美生子的中介机构。然而个中风险到底是怎样?

复旦大学附属中山医院肝肿瘤内科主任医师夏景林教授是小米的主治医生,他指出,虽然成功通过介入手术挽回了濒死的病患,但怀胎十月,孕妇每个月都应该有B超等身体检查,产妇竟然没有检查出肝癌,这让他陷入沉思。

小米还飞赴美国的妇产医院待产、生产,在美国有两个月左右时间,那么长时间,那么大的肿瘤,那么好的医疗水平,竟然到产后50天,回国半个月后因为感觉腹胀和出现黄疸,才在中山医院当天确诊。

临床上,基本的体格检查还是很有用的,产妇要是进行一个腹部体格检查应该就可以发现肝癌。”夏景林教授说。大部分病患都是已经出现了肝癌的症状或体征,自己觉得不舒服,或者自己能摸到腹部肿块、出现黄疸等情况才到医院就诊。到这个时候已经没有什么办法可以治疗了。

事实上,肝癌早期发现并不难。做个甲胎蛋白和B超检测,漏诊概率很低,可绝大部分有肝癌风险的人没有这个意识。

肝癌曾被称为“癌中之王”,通常晚期病患只能存活3-6个月,即便使用价格昂贵、国际公认有效的靶向药,其疗效也就延长2.8个月,而对于目前如火如荼的免疫治疗:PD-1来说,有效率也仅有15%。因此,晚期肝癌患者不管接受什么治疗,只要生存超过9个月,疗效就优于靶向药了。

“小米的家属来找我的时候,我没见到病人,因为病人体质虚弱且在中山医院急诊观察室接受输液。看了CT片子,看了病人的化验等资料。我就问了两句话:病人能起床吗?能吃饭吗?”得到肯定答案之后,夏景林告诉病患家属,“行,明天我就安排她住院。”

第二天,夏景林就给病患实施了介入手术。当导管将碘油和化疗药物打到到肝癌里面后,患者自觉腹胀减轻、黄疸逐步下降,顺利渡过低血钾、没出现肿瘤破裂、 肝功能衰竭、 肝肾综合征、肝肺综合征、溶瘤综合征(急性肾功能衰竭)感染消化道出血等危及生命的情况。

“但癌王可不会这么轻易束手就擒,病人术后有一个问题始终没有解决,心率一直在每分钟120次,而且病人体力、食欲恢复不理想。在排除感染心衰之后,我们分析,心率是因为胸水压迫造成肺不张所致。”

巨大肿瘤和产后因素,使病患根本经不起放胸水的消耗,但不控制胸腔积液,呼吸和心脏功能会逐步恶化,前面的治疗将前功尽弃。那天晚上,夏景林思量了一夜,天将亮就翻身起床,跑到医院跟病患商量——拼一把,置管放胸水,再往胸腔打化疗药,促使胸膜粘连。

病患对生命的坚持,家属积极配合并希望医生放手施救,一切又变得可能。时间走过了27天,年轻的母亲奇迹般走出医院,回到还在啼哭的婴儿身边……

这位赴美产子的妈妈如果按照目前国内外的诊疗常规:不能开刀、不能介入、不能放疗,基本上只能对症支持治疗,也就是用药减轻痛苦,但本质上难以延长生存。在目前医患关系紧张的大环境,其实很少有医生愿意冒这么大的风险去做手术。

“我们的挑战成功了,母亲的生命得以延续,家庭的幸福能够续写。活下去的每一天都很有意义!”夏景林教授说。这样的时刻是他作为医生最满足的一刻。

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    2018-09-04 青龙偃月

    好文章学习了!

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1526946, encodeId=f00a1526946b0, content=<a href='/topic/show?id=894221e3566' target=_blank style='color:#2F92EE;'>#中国医生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21735, encryptionId=894221e3566, topicName=中国医生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=45f511780919, createdName=nakerunner, createdTime=Wed Sep 05 14:00:00 CST 2018, time=2018-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342758, encodeId=c616342e58f4, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:34 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342757, encodeId=c0cf342e5795, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:29 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342756, encodeId=abc3342e565a, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:25 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342755, encodeId=6f70342e55fb, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:21 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342754, encodeId=bd39342e5401, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:17 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342753, encodeId=3373342e53d4, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:13 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342752, encodeId=4442342e529b, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:06 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342751, encodeId=bc0b342e514c, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:13:27 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342750, encodeId=abc1342e50ee, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:13:21 CST 2018, time=2018-09-04, status=1, ipAttribution=)]
    2018-09-04 青龙偃月

    好文章学习了!

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1526946, encodeId=f00a1526946b0, content=<a href='/topic/show?id=894221e3566' target=_blank style='color:#2F92EE;'>#中国医生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21735, encryptionId=894221e3566, topicName=中国医生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=45f511780919, createdName=nakerunner, createdTime=Wed Sep 05 14:00:00 CST 2018, time=2018-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342758, encodeId=c616342e58f4, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:34 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342757, encodeId=c0cf342e5795, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:29 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342756, encodeId=abc3342e565a, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:25 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342755, encodeId=6f70342e55fb, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:21 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342754, encodeId=bd39342e5401, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:17 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342753, encodeId=3373342e53d4, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:13 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342752, encodeId=4442342e529b, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:06 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342751, encodeId=bc0b342e514c, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:13:27 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342750, encodeId=abc1342e50ee, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:13:21 CST 2018, time=2018-09-04, status=1, ipAttribution=)]
    2018-09-04 青龙偃月

    好文章学习了!

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1526946, encodeId=f00a1526946b0, content=<a href='/topic/show?id=894221e3566' target=_blank style='color:#2F92EE;'>#中国医生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21735, encryptionId=894221e3566, topicName=中国医生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=45f511780919, createdName=nakerunner, createdTime=Wed Sep 05 14:00:00 CST 2018, time=2018-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342758, encodeId=c616342e58f4, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:34 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342757, encodeId=c0cf342e5795, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:29 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342756, encodeId=abc3342e565a, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:25 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342755, encodeId=6f70342e55fb, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:21 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342754, encodeId=bd39342e5401, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:17 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342753, encodeId=3373342e53d4, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:13 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342752, encodeId=4442342e529b, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:06 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342751, encodeId=bc0b342e514c, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:13:27 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342750, encodeId=abc1342e50ee, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:13:21 CST 2018, time=2018-09-04, status=1, ipAttribution=)]
    2018-09-04 青龙偃月

    好文章学习了!

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1526946, encodeId=f00a1526946b0, content=<a href='/topic/show?id=894221e3566' target=_blank style='color:#2F92EE;'>#中国医生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21735, encryptionId=894221e3566, topicName=中国医生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=45f511780919, createdName=nakerunner, createdTime=Wed Sep 05 14:00:00 CST 2018, time=2018-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342758, encodeId=c616342e58f4, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:34 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342757, encodeId=c0cf342e5795, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:29 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342756, encodeId=abc3342e565a, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:25 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342755, encodeId=6f70342e55fb, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:21 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342754, encodeId=bd39342e5401, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:17 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342753, encodeId=3373342e53d4, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:13 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342752, encodeId=4442342e529b, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:06 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342751, encodeId=bc0b342e514c, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:13:27 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342750, encodeId=abc1342e50ee, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:13:21 CST 2018, time=2018-09-04, status=1, ipAttribution=)]
    2018-09-04 青龙偃月

    好文章学习了!

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1526946, encodeId=f00a1526946b0, content=<a href='/topic/show?id=894221e3566' target=_blank style='color:#2F92EE;'>#中国医生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21735, encryptionId=894221e3566, topicName=中国医生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=45f511780919, createdName=nakerunner, createdTime=Wed Sep 05 14:00:00 CST 2018, time=2018-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342758, encodeId=c616342e58f4, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:34 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342757, encodeId=c0cf342e5795, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:29 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342756, encodeId=abc3342e565a, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:25 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342755, encodeId=6f70342e55fb, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:21 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342754, encodeId=bd39342e5401, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:17 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342753, encodeId=3373342e53d4, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:13 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342752, encodeId=4442342e529b, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:06 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342751, encodeId=bc0b342e514c, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:13:27 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342750, encodeId=abc1342e50ee, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:13:21 CST 2018, time=2018-09-04, status=1, ipAttribution=)]
    2018-09-04 青龙偃月

    好文章学习了!

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1526946, encodeId=f00a1526946b0, content=<a href='/topic/show?id=894221e3566' target=_blank style='color:#2F92EE;'>#中国医生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21735, encryptionId=894221e3566, topicName=中国医生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=45f511780919, createdName=nakerunner, createdTime=Wed Sep 05 14:00:00 CST 2018, time=2018-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342758, encodeId=c616342e58f4, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:34 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342757, encodeId=c0cf342e5795, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:29 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342756, encodeId=abc3342e565a, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:25 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342755, encodeId=6f70342e55fb, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:21 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342754, encodeId=bd39342e5401, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:17 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342753, encodeId=3373342e53d4, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:13 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342752, encodeId=4442342e529b, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:06 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342751, encodeId=bc0b342e514c, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:13:27 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342750, encodeId=abc1342e50ee, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:13:21 CST 2018, time=2018-09-04, status=1, ipAttribution=)]
    2018-09-04 青龙偃月

    好文章学习了!

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1526946, encodeId=f00a1526946b0, content=<a href='/topic/show?id=894221e3566' target=_blank style='color:#2F92EE;'>#中国医生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21735, encryptionId=894221e3566, topicName=中国医生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=45f511780919, createdName=nakerunner, createdTime=Wed Sep 05 14:00:00 CST 2018, time=2018-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342758, encodeId=c616342e58f4, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:34 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342757, encodeId=c0cf342e5795, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:29 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342756, encodeId=abc3342e565a, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:25 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342755, encodeId=6f70342e55fb, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:21 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342754, encodeId=bd39342e5401, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:17 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342753, encodeId=3373342e53d4, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:13 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342752, encodeId=4442342e529b, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:06 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342751, encodeId=bc0b342e514c, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:13:27 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342750, encodeId=abc1342e50ee, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:13:21 CST 2018, time=2018-09-04, status=1, ipAttribution=)]
    2018-09-04 青龙偃月

    好文章学习了!

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1526946, encodeId=f00a1526946b0, content=<a href='/topic/show?id=894221e3566' target=_blank style='color:#2F92EE;'>#中国医生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21735, encryptionId=894221e3566, topicName=中国医生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=45f511780919, createdName=nakerunner, createdTime=Wed Sep 05 14:00:00 CST 2018, time=2018-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342758, encodeId=c616342e58f4, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:34 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342757, encodeId=c0cf342e5795, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:29 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342756, encodeId=abc3342e565a, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:25 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342755, encodeId=6f70342e55fb, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:21 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342754, encodeId=bd39342e5401, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:17 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342753, encodeId=3373342e53d4, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:13 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342752, encodeId=4442342e529b, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:14:06 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342751, encodeId=bc0b342e514c, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:13:27 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342750, encodeId=abc1342e50ee, content=好文章学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160905/IMG57CD39B82D12E7926.jpg, createdBy=ac2c1946830, createdName=青龙偃月, createdTime=Tue Sep 04 21:13:21 CST 2018, time=2018-09-04, status=1, ipAttribution=)]
    2018-09-04 青龙偃月

    好文章学习了!

    0

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肝细胞癌(HCC)是最常见的原发性肝癌,严重危害人类健康。原发性肝癌的致病因素主要有肝炎病毒(HBV、HCV)的慢性感染、黄曲霉毒素暴露、嗜酒等,在我国是以乙型肝炎病毒为主。除了肿瘤的恶性特征外,肝癌由于起病隐匿,发现时患者往往已失去治疗机会,也是导致肝癌患者生存率差的重要因素。因此,如何早期发现肝癌一直是医学界所面临的重要挑战。

Cancer Lett:中科院大连化物所等揭示肝癌重要抑癌基因

中科院大连化物所生物技术研究部朴海龙团队与大连医科大学附属第一医院肝胆外科谭广团队合作,解释了肝癌细胞中去泛素化酶USP10的生物分子功能及分子机制。相关成果日前发表于《癌症快讯》杂志。

J Hepatol:在HCV患者抗病毒治疗后,开发出一种可以患者发生HCC风险的模型

HCC风险预测模型可做为工具,为个体患者制定基于HCC风险的监测策略提供了参考。