DIABETOLOGIA:孕妇糖尿病、妊娠期肥胖与儿童期超重或肥胖的母乳喂养之间的关系

2019-04-06 不详 网络

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本研究旨在探讨学龄前儿童母体糖尿病、孕龄偏大(LGA)和母乳喂养与超重或肥胖之间的相互关系。

20091月至20178月,对20051月至20138月出生与孕产妇住院和门诊记录和注册表数据包括的81226记录进行分析,包括学前阶段(4 - 6)身高和体重数据。同时对出生后5个月母乳喂养情况进行记录。根据孕妇孕期糖尿病状况(糖尿病、妊娠期糖尿病或既往糖尿病)和出生体重(适合妊娠年龄[AGA]LGA]),将儿童分为六类。采用世卫组织的标准用于确定超重或肥胖儿童。

结果显示,无糖尿病/AGA69,506(对照组),无糖尿病/LGA5926例,妊娠期糖尿病/AGA4563例,妊娠期糖尿病/LGA573例,既往糖尿病/AGA480例,既往糖尿病/LGA178例。学龄前儿童超重/肥胖发生率,对照组为20.5%,妊娠期糖尿病/LGA组为42.9%。仅LGA的校正可归因风险百分比(39.4%)显著高于妊娠期糖尿病(16.0%)或已存在糖尿病(15.1%);合并妊娠期糖尿病/LGA和既往糖尿病/LGA的风险,分别为50.1%39.1%。对既往糖尿病组进一步分层发现,1/AGA组超重/肥胖患病率为21.2%1/LGA组为31.4%(与无糖尿病组相似)2/AGA组为26.7%2/LGA组为42.5%。除妊娠期糖尿病/LGA和既往糖尿病/LGA(1型和2)外,母乳喂养与儿童期超重/肥胖的可能性较低。

与怀孕期间的孕妇糖尿病相比,LGA是儿童早期超重/肥胖风险的一个较为显著的指标。母亲患有妊娠期糖尿病或已有2型糖尿病的LGA儿童,其儿童期超重/肥胖发生率最高。在大多数儿童中,母乳喂养可降低儿童超重/肥胖的风险;然而,在患有糖尿病的母亲所生的LGA儿童中,这种联系没有得到持续验证。

原始出处:

Padma KaulSamantha L. BowkerAssociation between maternal diabetes, being large for gestational age and breast-feeding on being overweight or obese in childhood

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  5. 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  6. 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  7. 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  8. 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createdBy=0b7c20, createdName=wjcjjian, createdTime=Mon Apr 08 13:39:00 CST 2019, time=2019-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299606, encodeId=d083129960680, content=<a href='/topic/show?id=7a056349485' target=_blank style='color:#2F92EE;'>#母乳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63494, encryptionId=7a056349485, topicName=母乳)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1b289, createdName=villahu, createdTime=Mon Apr 08 13:39:00 CST 2019, time=2019-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1042363, encodeId=f92410423638d, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sun Apr 07 01:39:00 CST 2019, time=2019-04-07, status=1, ipAttribution=)]
    2019-04-08 villahu
  9. 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createdName=misszhang, createdTime=Sun Apr 07 01:39:00 CST 2019, time=2019-04-07, status=1, ipAttribution=)]
    2019-04-07 misszhang

    谢谢MedSci提供最新的资讯

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