Microbiome:母亲孕期饮食可能影响婴儿肠道微生物组成

2018-07-06 小通 生物通

《Microbiome》期刊报道,孕妇妊娠期间饮食影响婴儿肠道细菌群落,这种影响可能会伴随分娩方式改变。


《Microbiome》期刊报道,孕妇妊娠期间饮食影响婴儿肠道细菌群落,这种影响可能会伴随分娩方式改变。

该研究的第一作者Sara Lundgren说:“我们的研究表明,作为易于改变的因素,母亲的饮食对应婴儿肠道微生物群,这可能是开发基于孕妇和哺乳期妇女饮食指导建议的关键。”

Lundgren和达特茅斯医学中心的同事发现,分娩后六周内,婴儿的肠道菌群主要由肠杆菌科细菌(~20%)、双歧杆菌(18.6%)、拟杆菌(10.44%)和链球菌(8.1%)组成。

为了进一步了解母亲饮食通过肠道微生物群落影响婴儿健康的机制,作者采集了145名婴儿粪便样本以及母亲和婴儿的健康等信息,66.9%婴儿为阴道分娩,70.3%婴儿在6周龄前完全母乳喂养,研究人员通过调查问卷获得母亲在怀孕24至28周妊娠期间的饮食信息。

在这项研究中,作者鉴定出三种截然不同的微生物集群,在97例阴道分娩婴儿中,集群1的特点是双歧杆菌丰度高,集群2的特点是链球菌和梭菌丰度高,集群3的特点是拟杆菌丰度高。在48例剖腹产婴儿中,集群1仍为高双歧杆菌丰度,但集群2却表现出高梭菌丰度和低链球菌丰度,而集群3则是高丰度的肠杆菌。

作者观察到,母亲的饮食对婴儿的肠道微生物群存在某些方面的影响。在阴道分娩的婴儿中,母亲每天每增加一份水果,婴儿获得集群2的几率增加2.73倍。如果母亲吃更多水果,阴道分娩的婴儿的双歧杆菌就会减少。母亲食用红肉和加工肉类,剖腹产婴儿肠道双歧杆菌增多,在剖腹产分娩婴儿中,每天额外摄入1份奶制品的孕妇所产婴儿集群2几率增加2.36倍。

Lundgren说:“我们分析了阴道分娩和剖腹产婴儿,曾经我们认为产妇的微生物群转移只发生在阴道分娩,不涉及剖宫产。但是我们却更惊奇地发现,母体摄入的食物竟然对不同分娩类型产生不同影响。”

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  6. 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style='color:#2F92EE;'>#肠道微生物组#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81673, encryptionId=7ccf816e335, topicName=肠道微生物组)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c6316431503, createdName=snf701209, createdTime=Sun Jul 08 11:49:00 CST 2018, time=2018-07-08, status=1, ipAttribution=)]
    2018-07-15 jyzxjiangqin

    母亲孕期饮食可能影响婴儿肠道健康.

    0

  7. 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style='color:#2F92EE;'>#肠道微生物组#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81673, encryptionId=7ccf816e335, topicName=肠道微生物组)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c6316431503, createdName=snf701209, createdTime=Sun Jul 08 11:49:00 CST 2018, time=2018-07-08, status=1, ipAttribution=)]
    2018-07-10 大爰

    学习了谢谢分享!!

    0

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    2018-07-08 jyzxjiangqin

    母亲孕期饮食可能会有影响.丶

    0

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