J Periodontol: 肥胖儿童牙龈炎患者龈沟液、唾液抵抗素和肿瘤坏死因子-α水平

2018-08-19 MedSci MedSci原创

本研究旨在评估肥胖儿童牙龈炎患者龈沟液(GCF)和唾液中抵抗素和肿瘤坏死因子-α(TNF-α)的水平。

本研究旨在评估肥胖儿童牙龈炎患者龈沟液(GCF)和唾液中抵抗素和肿瘤坏死因子-α(TNF-α)的水平。

方法:本研究招募了130名儿童(65名肥胖者和65名正常体重;年龄8-12岁)。根据儿童的体重和牙周状况将儿童分为四个亚组; 1)患有牙龈炎的肥胖儿童(OG,n = 33); 2)健康牙周组织的肥胖儿童(OH,n = 32); 3)患有牙龈炎的正常体重的儿童(NWG,n = 32); 4)具有健康牙周组织的正常体重儿童(NWH,n = 33)。记录体重指数(BMI)百分位数,探诊深度(PPD),牙龈指数(GI)和菌斑指数(PI)。通过ELISA在GCF和唾液样本中分析抵抗素和TNF-α水平。

结果:肥胖儿童的BMI百分位数高于正常体重儿童(p <0.0001)。肥胖组和正常体重儿的PPD,GI,PI,GCF量,GCF,唾液抵抗素和TNF-α水平相似(P> 0.05)。 OG和NWG亚组具有显着更高的GI,PI,GCF量,GCF抵抗素总量和唾液抵抗素浓度,但GCF抵抗素和TNF-α浓度低于OH和NWH(所有人均P <0.0001)。 GCF抵抗素总量与GI,PI和GCF TNF-α总量呈正相关(P <0.05)。

患有牙龈炎的儿童,肥胖与GCF和唾液抵抗素和TNF-α水平无关。

原始出处:

Gulcin Dogusal, et al. Gingival crevicular fluid and salivary resistin and tumor necrosis factor‐alpha levels in obese children with gingivitis. Journal of Periodontology. 2018 August. doi:10.1002/JPER.17-0613

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    2019-05-10 feather89
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    2018-08-21 millore
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    2018-08-19 1e1b8538m79(暂无匿称)

    不错的文章值得拥有,

    0

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