Int Arch Allergy Immunol:年轻成年人中喘息和身体质量指数与常年和季节过敏性鼻炎的相关性分析

2018-06-04 AlexYang MedSci原创

哮喘和过敏性鼻炎(AR)的并存和与肥胖不同的相关关系已见报道。然而,很少有研究区分这两种类型的AR,即常年性(PAR)和季节性(SAR)与哮喘和肥胖之间的相关性。最近,有研究人员在日本年轻成年人中,评估了喘息与上述两种类型的AR的共存,以及身体质量指数(BMI)对这两种条件下的影响。研究发现,尽管PAR和SAR都与喘息显著相关,这两种类型的AR对喘息的影响是不同的(OR for PAR = 2.4

哮喘和过敏性鼻炎(AR)的并存和与肥胖不同的相关关系已见报道。然而,很少有研究区分这两种类型的AR,即常年性(PAR)和季节性(SAR)与哮喘和肥胖之间的相关性。最近,有研究人员在日本年轻成年人中,评估了喘息与上述两种类型的AR的共存,以及身体质量指数(BMI)对这两种条件下的影响。

研究发现,尽管PAR和SAR都与喘息显著相关,这两种类型的AR对喘息的影响是不同的(OR for PAR = 2.46 vs. OR for SAR = 1.29)。当研究人员将所有的参与者分成4个小组发现,喘息的流行度在患有PAR的小组中比那些不患有PAR的小组显著更高(p<0.001)。然而,喘息的流行度在患有或者不患有SAR的参与者中没有差别。多项式回归分析表明,患有PAR和/或者SAR的参与者与喘息的相关性要比那些患有喘息且患有SAR而不患有PAR的参与者显著更强。另外,PAR的流行度与BMI不相关。与之相反,低的BMI与搞的SAR流行度显著相关(p<0.05)。

最后,研究人员指出,PAR和SAR的比较表明了这两种AR与喘息和BMI存在着不同的相互关系。

原始出处:

Matsumoto M, Konno S, Kimura H et al. Associations of Current Wheeze and Body Mass Index with Perennial and Seasonal Allergic Rhinitis in Young Adults. Int Arch Allergy Immunol. 16 May 2018.

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    2018-06-06 膀胱癌
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    2018-06-06 30397606
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