世界血栓日:抗栓的十大更新,选择性门诊治疗急性肺栓塞似乎是安全的

2018-10-16 岱西 中国循环杂志

10月13日是世界血栓形成日。这个特别的日子里,HemOnc Today展现了当前血栓治疗、监测和风险预测等方面的十项更新。1.美国国家心、肺、血液研究所(NHLBI)给予克利夫兰诊所470万美元以开发出癌症相关静脉血栓栓塞更好的风险预测工具。2.接受即刻加压治疗的深静脉血栓患者,较之未接受者,显着降低残余静脉阻塞和血栓后综合征发生率;3.减重手术后的患者应用根据体重调整剂量的亭扎肝素来预防血栓是

10月13日是世界血栓形成日。这个特别的日子里,HemOnc Today展现了当前血栓治疗、监测和风险预测等方面的十项更新。

1.美国国家心、肺、血液研究所(NHLBI)给予克利夫兰诊所470万美元以开发出癌症相关静脉血栓栓塞更好的风险预测工具。

2.接受即刻加压治疗的深静脉血栓患者,较之未接受者,显着降低残余静脉阻塞和血栓后综合征发生率;

3.减重手术后的患者应用根据体重调整剂量的亭扎肝素来预防血栓是安全有效的,静脉血栓栓塞症(VTE)和大出血的发生率较低;

4.选择性门诊治疗急性肺栓塞似乎是安全的,死亡风险较低。在家中接受治疗的患者无死亡或复发性VTE;

5.与无肝病患者相比,中重度肝病患者VTE风险较低,但这些患者一旦在院内发生VTE则死亡风险增加;

6.与无VTE的女性相比,罹患VTE的女性体能急剧下降;

7.对于诊断为深静脉血栓(DVT)的急性期患者,压缩袜的应用可改善生活质量,且具有费效比;

8.尽管多层包扎似乎比压力袜更有效,但未改善生活质量,且成本较高;

9.围手术期红细胞输注似乎与术后新发生或进行性VTE相关;

10. 在高风险抗磷脂综合征患者中,利伐沙班与华法林相比,心脏事件风险增加。

来源:10 updates for World Thrombosis Day. October 12, 2018.

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    2019-01-12 13718711b3m

    学习了,值得借鉴的临床经验,获益匪浅,感谢分享!谢谢!

    0

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    2018-10-21 13718711b3m

    学习了,涨知识,非常不错的临床经验,值得借鉴,受益匪浅,感谢分享!

    0

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    2018-10-16 天地飞扬

    了解一下,谢谢分享!

    0

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嗜中性粒细胞外诱捕器(NETs)是由嗜中性粒细胞DNA产生的细胞外纤维网络,在感染、血栓形成和其他疾病中具有致病作用。目前人们期待可靠的测定NETs的方法,因为正在针探索对NETs的新疗法。本研究比较了全血流式细胞术与血清测定法,以测量脓毒症和血栓患者的NETs相关标志物。 研究中包括深静脉血栓形成(25例)、脓毒症(21例)和健康对照(n = 23)。通过控制染色的中性粒细胞染色(H3ci

Nat Med:抑制血栓形成:一种靶向肠道微生物的全新疗法

一种新药通过抑制肠道细菌产生特定化合物,从而显着降低心血管疾病的风险。

JACC:血栓抽吸不能改善高血栓风险STEMI患者预后

常规的血栓抽吸对接受经皮冠脉介入治疗(PCI)的ST段抬高型心梗(STEMI)患者来说并不会改善预后,但对有高血栓风险的该类患者来说是否有益尚不清楚。本研究的目的旨在评估血栓抽吸对伴高血栓风险的STEMI患者是否有益。本研究纳入的是TOTAL临床研究中的STEMI患者,主要终点事件是心源性死亡、心梗、心源性休克和心衰。分析结果显示,1年主要终点事件在接受血栓抽吸的高血栓风险STEMI患者和不接受抽