Obstet Gynecol:妊娠相关高血压和后代心脏代谢健康!

2018-01-12 xing.T MedSci原创

由此可见,妊娠相关高血压与足月产后代收缩压增高相关,而与舒张压、BMI、腰围、稳态模型评估的胰岛素抵抗、血糖或血脂无关。

近日,妇产科权威杂志Obstetrics and Gynecology上发表了一篇研究文章,研究人员旨在评估妊娠相关高血压(妊娠期高血压和先兆子痫)与年轻后代心脏代谢健康之间的相关。

这是一项前瞻性观察性随访研究,从2012年到2013年期间,其招募了参与轻度妊娠糖尿病治疗试验或非妊娠糖尿病观察性研究的妇女所生孩子。在出生后5-10年,研究人员对出生儿童进行了评估并收集了空腹血液样本,以明确下列心血管危险因素:血压(BP)、高密度脂蛋白胆固醇、甘油三酯、血糖、稳态模型评估的胰岛素抵抗、腰围和体重指数(BMI)。

这项分析纳入了979名儿童,评估时的年龄中位数为7岁。23名(2%)儿童为高血压妊娠的早产儿,73名(7%)儿童为足月高血压妊娠,58名(6%)儿童为正常妊娠早产儿,825名(84%)儿童为足月妊娠儿(参照组)。在调整混杂因素后,母亲为妊娠高血压的足月儿调整后的平均收缩压值显著高于母亲血压正常的足月儿(收缩压为104mmHg,95%可信区间为101-106;vs. 收缩压为99mmHg,95%可信区间为99-100,P=0.001)。未观察到其他显著差异。

由此可见,妊娠相关高血压与足月产后代收缩压增高相关,而与舒张压、BMI、腰围、稳态模型评估的胰岛素抵抗、血糖或血脂无关。

原始出处:

Rice Madeline Murguia, et al. Pregnancy-Associated Hypertension and Offspring Cardiometabolic Health.Obstetrics & Gynecology.2018. http://journals.lww.com/greenjournal/Abstract/publishahead/Pregnancy_Associated_Hypertension_and_Offspring.98175.aspx

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    2018-05-07 yhy100200
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    2018-01-17 虈亣靌

    认真学习.天天向上

    0

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    2018-01-15 15121100f4m

    有关的原因是什么呢?是遗传还是在外因素?

    0

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2018, time=2018-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=278177, encodeId=55ba2e817723, content=不错的文章值得推荐, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Jan 13 18:53:16 CST 2018, time=2018-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=278158, encodeId=d11c2e81588d, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJpBl6xwMmnsKibwxcAIltOH3nnCEQbNE6TDbYtCKe8hYI0oJrbduNqnJraM1PyyjPKU1suAzicYPaA/132, 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  8. 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2018, time=2018-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=278177, encodeId=55ba2e817723, content=不错的文章值得推荐, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Jan 13 18:53:16 CST 2018, time=2018-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=278158, encodeId=d11c2e81588d, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJpBl6xwMmnsKibwxcAIltOH3nnCEQbNE6TDbYtCKe8hYI0oJrbduNqnJraM1PyyjPKU1suAzicYPaA/132, createdBy=eeaf2031798, createdName=海之蓝, createdTime=Sat Jan 13 18:07:27 CST 2018, time=2018-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=277917, encodeId=cf0b2e7917ac, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/fhZdOu27e88Voqh19n8eF8cLplo8L4nicKtH0WnE3KFELXns5XDu8rsiceK2HHDZc2SEStia5VV3Pia2QLMVqlWbHw/0, createdBy=6e012139475, createdName=神功盖世, createdTime=Fri Jan 12 19:58:55 CST 2018, time=2018-01-12, status=1, ipAttribution=)]
    2018-01-13 虈亣靌

    不错的文章值得推荐

    0

  9. 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2018, time=2018-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=278177, encodeId=55ba2e817723, content=不错的文章值得推荐, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Jan 13 18:53:16 CST 2018, time=2018-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=278158, encodeId=d11c2e81588d, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJpBl6xwMmnsKibwxcAIltOH3nnCEQbNE6TDbYtCKe8hYI0oJrbduNqnJraM1PyyjPKU1suAzicYPaA/132, createdBy=eeaf2031798, createdName=海之蓝, createdTime=Sat Jan 13 18:07:27 CST 2018, time=2018-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=277917, encodeId=cf0b2e7917ac, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/fhZdOu27e88Voqh19n8eF8cLplo8L4nicKtH0WnE3KFELXns5XDu8rsiceK2HHDZc2SEStia5VV3Pia2QLMVqlWbHw/0, createdBy=6e012139475, createdName=神功盖世, createdTime=Fri Jan 12 19:58:55 CST 2018, time=2018-01-12, status=1, ipAttribution=)]
    2018-01-13 海之蓝

    学习

    0

  10. 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    2018-01-12 神功盖世

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