Prostate Cancer P D:核磁共振成像的术前分期和前列腺癌手术阳性手术切缘风险研究

2018-12-19 AlexYang MedSci原创

是否利用核磁共振成像(MRI)进行术前分期能够减少前列下癌阳性手术切缘的风险仍旧不清楚。最近,有研究人员评估了手术切缘的影响与术前MRI讨论中MRI呈现的骨盆神经保留程度。研究群体是一个单中心、观察性的群体,包括了2013年10月到2015年6月之间的1037名经历了机器人辅助根治性前列腺切除术的男性患者。其中,557名经历了术前MRI和术前MRI讨论,410名并没有经历上述过程。研究发现,MRI

是否利用核磁共振成像(MRI)进行术前分期能够减少前列下癌阳性手术切缘的风险仍旧不清楚。最近,有研究人员评估了手术切缘的影响与术前MRI讨论中MRI呈现的骨盆神经保留程度。

研究群体是一个单中心、观察性的群体,包括了2013年10月到2015年6月之间的1037名经历了机器人辅助根治性前列腺切除术的男性患者。其中,557名经历了术前MRI和术前MRI讨论,410名并没有经历上述过程。研究发现,MRI在80%的案例中检测到了指数肿瘤。在MRI组和非MRI组中,组织学非器官受限疾病(pT3)在2组中的占比分别为42%和24%。阳性手术切缘比例在MRI组和非MRI组中分别为26.7%和33.7%,相对风险0.79(95% CI 0.65-0.96)加权相对风险(wRR)0.69(95% CI 0.55-0.86)。广泛阳性手术切缘的wRR为0.45 (95% CI 0.31-0.67)。另外,经历MRI同样与进行非神经保留术风险的增加相关(wRR, 1.84 [95% CI 1.11-3.03])。

最后,研究人员指出,他们的研究表明了术前前列腺MRI组合术前MRI讨论能够影响神经保留术的程度和减少阳性手术切缘。

原始出处:

Fredrik Jäderling, Olof Akre, Markus Aly et al. Preoperative staging using magnetic resonance imaging and risk of positive surgical margins after prostate-cancer surgery. Prostate Cancer P D. 30 Nov 2018.

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  5. 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  6. 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    2018-12-21 lsndxfj
  7. 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  8. [GetPortalCommentsPageByObjectIdResponse(id=2055648, encodeId=dbae205564874, content=<a href='/topic/show?id=734110089320' target=_blank style='color:#2F92EE;'>#风险研究#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100893, encryptionId=734110089320, topicName=风险研究)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Sun Sep 08 00:05:00 CST 2019, time=2019-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2080774, encodeId=476f2080e7464, content=<a href='/topic/show?id=897254381a3' target=_blank style='color:#2F92EE;'>#手术切缘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54381, encryptionId=897254381a3, topicName=手术切缘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=69cb413, createdName=chengjn, createdTime=Sat Apr 27 08:05:00 CST 2019, time=2019-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1791562, encodeId=bad11e91562f6, content=<a href='/topic/show?id=b77f14e4541' target=_blank style='color:#2F92EE;'>#Prostate Ca#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14745, encryptionId=b77f14e4541, topicName=Prostate Ca)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a691420, createdName=30397604, createdTime=Fri Jun 21 07:05:00 CST 2019, time=2019-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1316606, encodeId=375c13166061e, content=<a href='/topic/show?id=ffb862113ca' target=_blank style='color:#2F92EE;'>#核磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62113, encryptionId=ffb862113ca, topicName=核磁共振)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=49cf452, createdName=xsm918, createdTime=Fri Dec 21 14:05:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341642, encodeId=50e713416423d, content=<a href='/topic/show?id=24b8e37529a' target=_blank style='color:#2F92EE;'>#磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73752, encryptionId=24b8e37529a, topicName=磁共振)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24a22500182, createdName=1696533704_45270454, createdTime=Fri Dec 21 14:05:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1364428, encodeId=004f136442831, content=<a href='/topic/show?id=7c5615628ad' target=_blank style='color:#2F92EE;'>#ROS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15628, encryptionId=7c5615628ad, topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Fri Dec 21 14:05:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506361, encodeId=29ca1506361a7, content=<a href='/topic/show?id=005d6211ed7' target=_blank style='color:#2F92EE;'>#核磁共振成像#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62117, encryptionId=005d6211ed7, topicName=核磁共振成像)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=061d9741590, createdName=yangcx0918, createdTime=Fri Dec 21 14:05:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1602097, encodeId=4e6d160209e06, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Fri Dec 21 14:05:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=355885, encodeId=ed503558853b, content=学习了,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Wed Dec 19 23:38:33 CST 2018, time=2018-12-19, status=1, ipAttribution=)]
    2018-12-21 sunylz
  9. 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    2018-12-19 惠映实验室

    学习了,谢谢分享。

    0

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