Obstet Gynecol:胎动计数与围产期死亡率

2020-01-20 xing.T MedSci原创

由此可见,指导孕妇如何进行胎动计数与没有指导相比,对妊娠结局无明显改善。与一些次要结局的关联较弱,例如早产、引产和剖宫产。

近日,妇产科权威杂志Obstetrics and Gynecology上发表了一研究文章,研究人员旨在评估胎儿运动计数与围产期死亡率之间的关联。

研究人员检索了电子数据库(即MEDLINE、ClinicalTrials.gov、ScienceDirect、Central对照试验登记册的Cochrane图书馆),检索时间从数据库成立到2019年5月。使用的检索词为:“胎儿运动”、“胎儿运动计数”、“胎儿踢腿次数”、“死产”、“胎儿死亡”、“胎儿死亡率”和“围产期死亡”。研究人员纳入了所有比较了随机接受胎儿运动计数指导的那些妇女与没有接受指导的对照组妇女围产期死亡率的随机对照试验。该研究的主要结局为围产期死亡率。

研究人员确定的1290篇文献中的5篇包含468601名胎儿。胎儿运动减少的定义各不相同。在五项研究中的四项,干预组中的妇女被要求与她们的医疗保健提供者联系,如果她们认为胎儿的活动减少;第五项研究未提供细节。报道的胎儿运动减少通常会进行电子胎儿监护和超声评估胎儿的健康状况。两组之间围产期结局的发生率无差异。胎动计数组围产期死亡的发生率为0.54%(1252/229943),对照组为0.59%(944/159755)(相对危险度[RR]为0.92,95%CI为0.85-1.00)。其他围产期结局无统计学差异,如死产、新生儿死亡、出生体重低于10%、报告胎儿运动减少、5分钟Apgar评分低于7分、新生儿入住重症监护病房或围产期发病率。早产分娩率(7.6% vs. 7.1%; RR为1.07,95%CI为1.05-1.10)、引产(36.6% vs. 31.6%; RR为1.15,95%CI为1.09-1.22)和剖宫产(28.2% vs. 25.3%;RR为1.11,95%CI为1.10-1.12)轻微增加,但有统计学差异。

由此可见,指导孕妇如何进行胎动计数与没有指导相比,对妊娠结局无明显改善。与一些次要结局的关联较弱,例如早产、引产和剖宫产。

原始出处:

Bellussi, Federica,et al.Fetal Movement Counting and Perinatal Mortality A Systematic Review and Meta-analysis.Obstetrics & Gynecology.2020.https://journals.lww.com/greenjournal/Abstract/publishahead/Fetal_Movement_Counting_and_Perinatal_Mortality__A.97486.aspx

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