Stroke:行动起来!提高心肺适能可降低卒中风险

2018-12-14 国际循环编辑部 国际循环

心肺适能低与心血管风险增加相关,近日,Stroke的一项最新研究旨在评估随时间改变的心肺适能是否对卒中和死亡的长期风险有影响。

心肺适能低与血管风险增加相关,近日,Stroke的一项最新研究旨在评估随时间改变的心肺适能是否对卒中和死亡的长期风险有影响。

研究纳入1972年~1975年40~59岁的2014名健康男性,随访至2007年。通过将总运动量除以体重,在基线和7年时运用心电图测试评估心肺适能状况。根据适能是否保持或超过随访期间的中位值,将参与者分为保持适应、变得不适应、保持不适应或变得适应组。收集研究随访、医院记录和国家死因登记处长达35年的结果数据。通过Cox回归分析评估卒中和死亡风险,平均随访23.6年。

对1403名参与者的基线和7年再次评估结果表明,与变得不适应组相比,卒中风险保持不适应组为0.85(0.54~1.36),保持适应组为0.43(0.28~0.67),变得适应组为0.34(0.17~0.67)。全因死亡,风险分别为0.99(0.76~1.29),0.57(0.45~0.74)和0.65(0.46~0.90)。此外,基线心肺适应性较高的人群中,变得不适应组的卒中风险(HR=2.35;95%CI:1.49~3.63)和死亡风险(HR=1.74;95%CI:1.35~2.23)显著高于保持适应组。在基线心肺适能较低的患者中,适应组患者的卒中风险(HR=0.40;95%CI:0.21~0.72)和死亡风险(HR=0.66;95%CI:0.50~0.85)显著低于其余不适应组患者。

基线时心肺适能和适能的变化与卒中和死亡的长期风险变化相关。因此,该研究结果支持鼓励经常锻炼作为卒中预防策略。

原始出处:
Erik Prestgaard, Julian Mariampillai, Kristian Engeseth, et al. Change in Cardiorespiratory Fitness and Risk of Stroke and Death. Stroke. Dec 2018.

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    2018-12-14 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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    2018-12-14 guging

    中风是俗称,应该称为缺血性卒中吧

    0

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