Ann Intern Med:60岁或以上老人高血压药物治疗的目标:ACP和AAFP的临床实践指南

2017-04-21 门鹏;吴刚 环球医学

高血压是美国非常常见的慢性疾病。美国成人的高血压总患病率为29.0%,60岁或以上老年人则增加到64.9%。2017年3月,《Ann Intern Med》上发布了60岁或以上老人高血压药物治疗的目标为较高还是较低的血压目标:美国内科医师学会和美国家庭医师学会的临床实践指南。描述:美国内科医师学会(ACP)和美国家庭医师学会(AAFP)基于60岁或以上老年人高血压治疗的较高vs较低血压目标的风险和


高血压是美国非常常见的慢性疾病。美国成人的高血压总患病率为29.0%,60岁或以上老年人则增加到64.9%。2017年3月,《Ann Intern Med》上发布了60岁或以上老人高血压药物治疗的目标为较高还是较低的血压目标:美国内科医师学会和美国家庭医师学会的临床实践指南。

描述:美国内科医师学会(ACP)和美国家庭医师学会(AAFP)基于60岁或以上老年人高血压治疗的较高vs较低血压目标的风险和获益,共同制定了该指南,旨在呈现证据并提供临床建议。

方法:该指南的制定是基于截至2015年1月发表的随机对照试验的首要结局和观察性研究的仅危害性结局的系统评价,检索的数据库为Embase、Cochrane系统评价数据库、Medline和ClinicalTrials.gov,其中,Medline的检索更新到2016年9月。评估的结局包括全因死亡率、与卒中、严重心脏事件(致命性和非致命性心肌梗死和心脏性猝死)和危害相关的发病率和死亡率。该指南使用GRADE(推荐评估、发展和评价分级)方法对证据和建议进行分级。

目标受众与患者人群:本指南的目标受众包括所有的医生,针对的患者人群包括所有60岁或以上的高血压老年患者。

建议1:ACP和AAFP建议,对于收缩压持续处于或高于150mmHg的60岁或以上患者,医生的初始治疗应实现目标收缩压低于150mmHg,以降低死亡、卒中和心脏事件的风险(等级:强烈建议,高质量证据)。ACP和AAFP建议,医生为60岁或以上的高血压患者选择治疗目标应基于周期性评估此类患者具体血压目标的风险和获益。

建议2:ACP和AAFP建议,对于60岁或以上的具有卒中或短暂性脑缺血发作史的患者,医生的初始或强化药物治疗应实现目标收缩压低于140mmHg,以降低卒中复发风险(等级:弱建议,中等质量证据)。ACP和AAFP建议,医生为60岁或以上的高血压患者选择治疗目标应基于周期性评估此类患者具体血压目标的风险和获益。

建议3:ACP和AAFP建议,对于一些60岁或以上的基于个体评估得出的处于较高心血管风险的患者,医生可考虑初始或强化药物治疗的目标为实现目标收缩压低于140mmHg,以降低卒中或心脏事件风险(等级:弱建议,低质量证据)。ACP和AAFP建议,医生为60岁或以上的高血压患者选择治疗目标应基于周期性评估此类患者具体血压目标的风险和获益。

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    2017-10-13 waiwai3042
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    2017-11-27 mxj1971619
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    2017-04-22 1ddf0692m34(暂无匿称)

    涨知识,学习了!

    0

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    2017-04-22 大爰

    新观点,学习了!

    0

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    2017-04-21 有备才能无患

    老年人血压没什么并发症的维持在14090左右

    0

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