Gastroenterology:颠覆认知!你以为是麸质导致乳糜泻?其实是果聚糖!

2017-11-15 vironia,Juka 转化医学网

近日,挪威奥斯陆大学和澳大利亚莫纳什大学研究人员发现,许多人在吃完含小麦食物后所产生的胃部胀气可能是由于对果聚糖的过度敏感,而并非为人们所普遍熟知的麸质。该研究对应文章则发表于最新上线的“胃肠病学”杂志(Gastroenterology),题为“Fructan, Rather Than Gluten, Induces Symptoms in Patients With Self-reported

近日,挪威奥斯陆大学和澳大利亚莫纳什大学研究人员发现,许多人在吃完含小麦食物后所产生的胃部胀气可能是由于对果聚糖的过度敏感,而并非为人们所普遍熟知的麸质。该研究对应文章则发表于最新上线的“胃肠病学”杂志(Gastroenterology),题为“Fructan, Rather Than Gluten, Induces Symptoms in Patients With Self-reported Non-celiac Gluten Sensitivity”。

研究人员通过对志愿者的含果聚糖或麸质饮食研究证实了“麸质”并非引起人们胃肠过敏的罪魁祸首。

最近几年,人类对于谷蛋白存在敏感的事实已然发展成为一种全球趋势。多达13%的人在吃完含有麸质的食物后会感到腹胀,因此很多人开始寻求无麸质食物。但是现在看来,除了严重的过敏反应之外,这种单纯认为麸质引起腹胀的想法极可能是错误的。

根据这项最新的研究,许多人完全不用寻找无麸质食物,他们真正应该寻找的是无果聚糖食物。

果聚糖由多个葡萄糖分子通过β-糖甘键连接而成。由于人体中不含有能分解果聚糖的酶,因此不能消化吸收果聚糖。

通常情况下,果聚糖大量存在于小麦,洋葱,大蒜和其他一些蔬菜中。

先前的研究发现果聚糖与肠易激综合征症状之间可能存在联系。正因为如此,研究人员想知道果聚糖是否同样在一些轻度的胃肠道问题中扮演者什么角色。

为了找到答案,他们招募了59名自我诊断为麸质不耐症的人,研究人员将参与者分为了三组,在实验进行的几个星期中分别给予含麸质不含果聚糖,含果聚糖不含麸质以及同时不含果聚糖及麸质的麦棒食用。研究人员对参与者食用特定麦棒后的具体症状进行了观察和记录。

研究结果表明,这些自我诊断为麸质不耐症的人只有在吃含果聚糖的麦棒时才会经历那些他们所熟悉的腹胀。当食用含麸质和对照组麦棒时,他们并没有出现任何腹胀的感觉。研究人员认为,这一现象表明引起大多数人们在食用谷物食物后发生腹胀的罪魁祸首并不是人们印象中的麸质,而是并没有得到人们足够重视的果聚糖。

研究人员认为这一发现非常重要,他们指出,使用无麸质饮食的人患上二型糖尿病的风险会上升许多。乳糜泻和小麦过敏之外的小麦敏感人群并不需要对麸质望而生畏,他们真正需要关注的很可能是以往被严重忽视的果聚糖。

原始出处:

Skodje GI,et al.,Fructan, Rather Than Gluten, Induces Symptoms in Patients With Self-reported Non-celiac Gluten Sensitivity.Gastroenterology. 2017 Nov 1. pii: S0016-5085(17)36302-3.

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    2018-01-22 许安
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    2017-12-23 情途末路

    学习了.获益匪浅!感谢分享

    0

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    2017-11-29 jyzxjiangqin

    乳糜泻的治疗.

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    2017-11-25 jyzxjiangqin

    果聚糖的相关知识.

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