Brit J Cancer：中国成人肥胖与结肠直肠癌和小肠癌的风险！

2018-06-08 xing.T MedSci原创

由此可见，在相对精瘦的中国成年人中，肥胖与结肠癌和直肠癌的风险相关，男性比女性相关性更密切。

关于肥胖与中国肠癌及其解剖亚型之间的关联仍然存在不确定性。近日，肿瘤领域权威杂志British Journal of Cancer上针对这一问题发表了一篇研究文章。

在10年随访期间，对于509568名基线时无癌症的参与者，中国前瞻性的Kadoorie生物库中记录了3024例结肠直肠癌（CRC）患者和143例小肠癌（SIC）癌患者。研究人员采用Cox回归分析估计了与肥胖相关的特定癌症调整后的风险比（HRs）。

总体平均体重指数（BMI）为23.7kg/m2。BMI与CRC（每增加一个SD风险比为1.10（95%CI为1.06-1.14））、结肠（1.13（1.07-1.18））和直肠癌（1.07（1.02-1.13））呈正相关。对于腰围，每增加一个SD对应的风险比分别为1.14（1.10-1.18）、1.18（1.13-1.24）和1.11（1.05-1.16）。男性调整后的HRs比女性略高。肥胖与SIC风险呈正相关，但不显著。

由此可见，在相对精瘦的中国成年人中，肥胖与结肠癌和直肠癌的风险相关，男性比女性相关性更密切。

原始出处：

Yuanjie Pang,et al. Adiposity and risks of colorectal and small intestine cancer in Chinese adults: a prospective study of 0.5 million people.British Journal of Cancer. 2018. https://www.nature.com/articles/s41416-018-0124-8

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2019-05-08 lfyang

#小肠癌#

31 0
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2018-11-28 bbwznl

#成人肥胖#

37 0
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2018-06-18 溜溜梅不酸

在相对精瘦的中国成年人中.肥胖与结肠癌和直肠癌的风险相关.男性比女性相关性更密切.

65 0
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2018-06-11 121832a9m88暂无昵称

学习了

57 0
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2018-06-10 lmm403

#结肠直肠癌#

28 0
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2018-06-10 phoebeyan520

学习了受益匪浅!

58 0
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2018-06-08 1e0f8808m18(暂无匿称)

减肥降低消化道癌症风险.

60 0
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2018-06-08 龙胆草

学习谢谢分享

60 0

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