BMC Urol:达泊西汀治疗在中国早泄患者中的疗效以及在现实生活中可能影响疗效的因素

2020-02-27 不详 网络

达泊西汀在现实世界中的治疗效果尚不明确。本眼距旨在探讨在实际环境中影响达泊西汀治疗早泄(PE)疗效的因素。2015年1月至2015年12月期间,研究人员对154例患者进行了随访。临床总体变化印象(CGIC),早泄概况(PEP),估计的阴道内射精潜伏时间(eIELT)和估计的射精前阴道内推力次数(NITBE)被收集。比较CGIC = 0和CGIC≥1的患者的临床特征。结果显示,治疗4周后,平均eIE

达泊西汀在现实世界中的治疗效果尚不明确。本眼距旨在探讨在实际环境中影响达泊西汀治疗早泄(PE)疗效的因素。

2015年1月至2015年12月期间,研究人员对154例患者进行了随访。临床总体变化印象(CGIC),早泄概况(PEP),估计的阴道内射精潜伏时间(eIELT)和估计的射精前阴道内推力次数(NITBE)被收集。比较CGIC = 0和CGIC≥1的患者的临床特征。

结果显示,治疗4周后,平均eIELT(2.4±±1.6 min vs 1.0±±0.7 min,P <0.001)和平均NITBE(85.9±61.9倍对37.4±28.6倍,P <0.001)与基线相比有明显改善。自我评价至少为“略好”并被分类为“CGIC≥1”组的患者比例为70.1%。基线时,“CGIC = 0”和“CGIC≥1”组患者的平均NITBE(P = 0.010)和PEDT(P = 0.009)得分之间存在显著差异。不良反应是可以接受的。

综上所述,该研究结果表明,达泊西汀具有良好的耐受性,可改善PE患者的性满足感。基于PEDT和NITBE的PE严重程度表明,在实际应用中,使用达泊西汀可能会改变疗效。

原始出处:

Jing Peng,#1 Dong Fang, et al., Efficacy of dapoxetine treatment in Chinese patients with premature ejaculation and possible factors affecting efficacy in the real-world practice. BMC Urol. 2020; 20: 11. doi: 10.1186/s12894-020-0580-3

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    2021-10-01 ms9000001217739185

    重度早泄效果不佳

    0

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    2020-02-27 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0