Diabetes Care:春节期间,你还在熬夜么?!

2018-02-17 MedSci MedSci原创

近期,一项发表在杂志Diabetes care上的研究评估了过去和现在的夜班工作以及遗传性2型糖尿病易感性对2型糖尿病发生率的影响。此项研究在英国的生物样本库中,评估了当前(N = 272,214)和终生(N = 70,480)夜班工作暴露与2型糖尿病风险(分别为6,770例和1,191例流行病例)之间的相关性。对180,704名和44,141名无血缘关系的欧洲血统参与者(分别为4,002和726

近期,一项发表在杂志Diabetes care上的研究评估了过去和现在的夜班工作以及遗传性2型糖尿病易感性对2型糖尿病发生率的影响。

此项研究在英国的生物样本库中,评估了当前(N = 272,214)和终生(N = 70,480)夜班工作暴露与2型糖尿病风险(分别为6,770例和1,191例流行病例)之间的相关性。对180,704名和44,141名无血缘关系的欧洲血统参与者(分别为4,002和726例)的基因数据进行了评估,评估轮班工作暴露是否修改了2型糖尿病遗传风险评分(包含110个单核苷酸多态性)和流行糖尿病之间的关系。

此项研究结果显示:与日间工作者相比,所有目前的夜班工作者对2型糖尿病的多变量调整后优势比增高(无或较少夜班:比值比[OR] 1.15 [95%CI 1.05-1.26];罕见夜班:OR 1.18 [95 %CI 1.05-1.32];经常晚上:OR 1.44 [95%CI 1.19-1.73]),除外目前的永久夜班工作(OR 1.09 [95%CI 0.93-1.27])。

考虑到一个人一生的工作时间表,并与从不换班的员工进行比较,每月工作更多夜班与更高的2型糖尿病发生率相关(<3/月:OR 1.24 [95%CI 0.90-1.68];3-8/月: OR 1.11 [95%CI 0.90-1.37];> 8 /月:OR 1.36 [95%CI 1.14-1.62]; Ptrend = 0.001)。轮班工作未改变遗传性2型糖尿病易感性与2型糖尿病概率之间的关联。

此项研究结果表明:夜班工作,尤其是包括夜班的轮班工作与2型糖尿病的发生率较高相关,每月工作的夜班次数与2型糖尿病发生率最相关。此外,轮班工作并不能改变2型糖尿病的遗传风险。

原始出处:
Vetter C, Dashti HS, et al. Night Shift Work, Genetic Risk, and Type 2 Diabetes in the UK Biobank. Diabetes Care. 2018 Feb 12. pii: dc171933. doi: 10.2337/dc17-1933.

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    2018-02-20 惠映实验室

    学习.谢谢分享.

    0

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    2018-02-19 guozhenyu
  6. [GetPortalCommentsPageByObjectIdResponse(id=1638422, encodeId=96b61638422cf, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Apr 19 17:36:00 CST 2018, time=2018-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1760541, encodeId=ed161e60541a4, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Mon Oct 01 06:36:00 CST 2018, time=2018-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901982, encodeId=a856190198277, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Fri Feb 23 03:36:00 CST 2018, time=2018-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289404, encodeId=ac65289404a3, content=学习.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Tue Feb 20 08:55:18 CST 2018, time=2018-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385733, encodeId=291e1385e3331, content=<a href='/topic/show?id=526259e00c1' target=_blank style='color:#2F92EE;'>#春节#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59700, encryptionId=526259e00c1, topicName=春节)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc4b507, createdName=guozhenyu, createdTime=Mon Feb 19 02:36:00 CST 2018, time=2018-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288731, encodeId=1dbf288e31a4, content=学习.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Feb 17 21:02:10 CST 2018, time=2018-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288717, encodeId=3ba9288e174f, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Feb 17 18:43:57 CST 2018, time=2018-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288711, encodeId=5962288e1168, content=现在很少熬夜打牌了.由于工作忙.值班必须熬夜.没办法., beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Sat Feb 17 18:13:13 CST 2018, time=2018-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288699, encodeId=085428869995, content=好文章.学习了., beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sat Feb 17 15:58:28 CST 2018, time=2018-02-17, status=1, ipAttribution=)]
    2018-02-17 惠映实验室

    学习.谢谢分享.

    0

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    2018-02-17 虈亣靌

    学习了谢谢分享!!

    0

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    2018-02-17 邓启付

    现在很少熬夜打牌了.由于工作忙.值班必须熬夜.没办法.

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1638422, encodeId=96b61638422cf, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Apr 19 17:36:00 CST 2018, time=2018-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1760541, encodeId=ed161e60541a4, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Mon Oct 01 06:36:00 CST 2018, time=2018-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901982, encodeId=a856190198277, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Fri Feb 23 03:36:00 CST 2018, time=2018-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289404, encodeId=ac65289404a3, content=学习.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Tue Feb 20 08:55:18 CST 2018, time=2018-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385733, encodeId=291e1385e3331, content=<a href='/topic/show?id=526259e00c1' target=_blank style='color:#2F92EE;'>#春节#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59700, encryptionId=526259e00c1, topicName=春节)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc4b507, createdName=guozhenyu, createdTime=Mon Feb 19 02:36:00 CST 2018, time=2018-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288731, encodeId=1dbf288e31a4, content=学习.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Feb 17 21:02:10 CST 2018, time=2018-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288717, encodeId=3ba9288e174f, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Feb 17 18:43:57 CST 2018, time=2018-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288711, encodeId=5962288e1168, content=现在很少熬夜打牌了.由于工作忙.值班必须熬夜.没办法., beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Sat Feb 17 18:13:13 CST 2018, time=2018-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288699, encodeId=085428869995, content=好文章.学习了., beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sat Feb 17 15:58:28 CST 2018, time=2018-02-17, status=1, ipAttribution=)]
    2018-02-17 1e0f8808m18(暂无匿称)

    好文章.学习了.

    0

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