BJS:系统评价减肥手术后糖尿病的风险预测模型

2016-10-18 MedSci MedSci原创

糖尿病缓解是减肥手术后的一个重要的结果。本研究的目的是确定减肥手术后糖尿病缓解的风险预测模型。对Medline、MEDLINE‐In‐Process、EMBASE和Cochrane对照实验数据库进行检索,截止2015年4月,纳入减肥手术后糖尿病结局风险因素的开发和验证研究。数据提取包括人口统计学、结局、变量、模型区别和校准。检索到的2330项研究中,8项符合纳入标准。其中,6项提出了开发风险预测模

糖尿病缓解是减肥手术后的一个重要的结果。本研究的目的是确定减肥手术后糖尿病缓解的风险预测模型。

对Medline、MEDLINE‐In‐Process、EMBASE和Cochrane对照实验数据库进行检索,截止2015年4月,纳入减肥手术后糖尿病结局风险因素的开发和验证研究。数据提取包括人口统计学、结局、变量、模型区别和校准。


检索到的2330项研究中,8项符合纳入标准。其中,6项提出了开发风险预测模型,2项对现有模型进行了验证。所有纳入模型均用于预测糖尿病缓解情况。一个模型报告称用了十倍验证进行内部验证。两个模型(ABCD评分和DiaRem评分)使用独立的病人,分别在术后12个月和14个月糖尿病缓解,进行外部验证。八个研究中有11个队列,在任何队列中都没有报道校准,2项报告了模型的区别。

目前可预测减肥手术后糖尿病风险的模型很多,但是只有2个模型经历了外部验证的检验。

原始出处:


R. Zhang, O. Borisenko, I. Telegina, J. Hargreaves, A. R. Ahmed, R. Sanchez Santos, C. Pring, P. Funch‐Jensen, B. Dillemans, J. L. Hedenbro.Systematic review of risk prediction models for diabetes after bariatric surgery.BJS.Volume 103 Issue 11 (October 2016)

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    2016-10-20 huagfeg
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