BMC Complement Altern Med:印楝提取物或可用于牙周病的治疗

2018-05-09 MedSci MedSci原创

印度楝树制备的咀嚼棒或可用于牙周疾病的治疗。本研究旨在探讨印楝叶提取物对牙龈卟啉单胞菌和牙髓有丝分裂菌的抗菌作用及其抗氧化能力,以及与可能在炎症部位的细菌和聚阳离子肽的结合。 通过乙醇提取制备印楝叶提取物。厌氧环境中,在Neem叶提取物存在下评估P.gingivalis和F. nucleatum的生长。肉汤微量稀释试验用于确定印楝叶提取物对每种细菌菌株的最小抑制浓度(MIC)。通过视觉半定量

印度楝树制备的咀嚼棒或可用于牙周疾病的治疗。本研究旨在探讨印楝叶提取物对牙龈卟啉单胞菌和牙髓有丝分裂菌的抗菌作用及其抗氧化能力,以及与可能在炎症部位的细菌和聚阳离子肽的结合。

通过乙醇提取制备印楝叶提取物。厌氧环境中,在Neem叶提取物存在下评估P.gingivalis和F. nucleatum的生长。肉汤微量稀释试验用于确定印楝叶提取物对每种细菌菌株的最小抑制浓度(MIC)。通过视觉半定量测定评估印楝叶提取物对细菌共凝集作用的影响。使用化学发光测定法测定单独和与细菌组合的印楝叶提取物的抗氧化能力,加入红细胞或聚阳离子肽氯己定和去氧酶。

结果显示,印楝叶提取物对P.gingivalis具有明显的剂量依赖性抗菌活性,但对F. nucleatum的生长和两种细菌的共凝集作用没有影响。但是,印楝叶提取物显示出强烈的抗氧化活性,且在粘附细菌并且添加红细胞或聚阳离子肽后这种效果更加明显。

总之,印楝叶提取物含有粘附于口腔表面的多酚,当与细菌、红血细胞和利斯霉酶复合时,具有提供长效抗菌以及协同抗氧化活性的潜力。因此,其或在治疗牙周疾病中特别有效。

原始出处:

Heyman L, Houri-Haddad Y, et al., Combined antioxidant effects of Neem extract, bacteria, red blood cells and Lysozyme: possible relation to periodontal disease. BMC Complement Altern Med. 2017 Aug 10;17(1):399. doi: 10.1186/s12906-017-1900-3.

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    2019-02-13 xuyong536
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    2019-02-07 zsyan
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href='/topic/show?id=46a06e5220c' target=_blank style='color:#2F92EE;'>#牙周病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67522, encryptionId=46a06e5220c, topicName=牙周病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1376173, createdName=linagood, createdTime=Fri May 11 11:11:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450875, encodeId=ac5d14508e57d, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Fri May 11 11:11:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608810, encodeId=3e211608810e3, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri May 11 11:11:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313903, encodeId=1f673139039c, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6b0d1671629, createdName=1de11f7fm56(暂无匿称), createdTime=Thu May 10 21:59:47 CST 2018, time=2018-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313888, encodeId=bf503138886a, content=好好好好学习天天向上好, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQpl0ENSJScphsFtdgfibXX1g1IuEYGCjP23UqCd52TxTpSZibtPiclyusaHicnNXd78alaia19Qy1nAFo18/0, createdBy=50381491660, createdName=zwjnj2, createdTime=Thu May 10 20:48:17 CST 2018, time=2018-05-10, status=1, ipAttribution=)]
    2018-08-16 shizhenshan
  5. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608810, encodeId=3e211608810e3, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri May 11 11:11:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313903, encodeId=1f673139039c, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6b0d1671629, createdName=1de11f7fm56(暂无匿称), createdTime=Thu May 10 21:59:47 CST 2018, time=2018-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313888, encodeId=bf503138886a, content=好好好好学习天天向上好, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQpl0ENSJScphsFtdgfibXX1g1IuEYGCjP23UqCd52TxTpSZibtPiclyusaHicnNXd78alaia19Qy1nAFo18/0, createdBy=50381491660, createdName=zwjnj2, createdTime=Thu May 10 20:48:17 CST 2018, time=2018-05-10, status=1, ipAttribution=)]
    2019-02-09 w363522449
  6. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608810, encodeId=3e211608810e3, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri May 11 11:11:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313903, encodeId=1f673139039c, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6b0d1671629, createdName=1de11f7fm56(暂无匿称), createdTime=Thu May 10 21:59:47 CST 2018, time=2018-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313888, encodeId=bf503138886a, content=好好好好学习天天向上好, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQpl0ENSJScphsFtdgfibXX1g1IuEYGCjP23UqCd52TxTpSZibtPiclyusaHicnNXd78alaia19Qy1nAFo18/0, createdBy=50381491660, createdName=zwjnj2, createdTime=Thu May 10 20:48:17 CST 2018, time=2018-05-10, status=1, ipAttribution=)]
  7. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313888, encodeId=bf503138886a, content=好好好好学习天天向上好, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQpl0ENSJScphsFtdgfibXX1g1IuEYGCjP23UqCd52TxTpSZibtPiclyusaHicnNXd78alaia19Qy1nAFo18/0, createdBy=50381491660, createdName=zwjnj2, createdTime=Thu May 10 20:48:17 CST 2018, time=2018-05-10, status=1, ipAttribution=)]
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  9. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313888, encodeId=bf503138886a, content=好好好好学习天天向上好, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQpl0ENSJScphsFtdgfibXX1g1IuEYGCjP23UqCd52TxTpSZibtPiclyusaHicnNXd78alaia19Qy1nAFo18/0, createdBy=50381491660, createdName=zwjnj2, createdTime=Thu May 10 20:48:17 CST 2018, time=2018-05-10, status=1, ipAttribution=)]
    2018-05-10 1de11f7fm56(暂无匿称)

    学习了.谢谢分享

    0

  10. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608810, encodeId=3e211608810e3, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri May 11 11:11:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313903, encodeId=1f673139039c, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6b0d1671629, createdName=1de11f7fm56(暂无匿称), createdTime=Thu May 10 21:59:47 CST 2018, time=2018-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313888, encodeId=bf503138886a, content=好好好好学习天天向上好, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQpl0ENSJScphsFtdgfibXX1g1IuEYGCjP23UqCd52TxTpSZibtPiclyusaHicnNXd78alaia19Qy1nAFo18/0, createdBy=50381491660, createdName=zwjnj2, createdTime=Thu May 10 20:48:17 CST 2018, time=2018-05-10, status=1, ipAttribution=)]
    2018-05-10 zwjnj2

    好好好好学习天天向上好

    0