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BMJ：疱疹样皮肤转移-案例报道

2017-05-09 xing.T MedSci原创

乳腺癌疱疹样皮肤转移
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活检结果显示为乳腺癌皮肤转移。在女性恶性肿瘤中，乳腺癌发现皮肤转移更为常见。它们发生皮肤转移时最常见部位为癌灶同侧胸壁皮肤。

患者为一名46岁的女性，既往被诊断为乳腺癌两年，在其左前胸部乳房切除术手术部位上方出现了无症状的皮疹（如图1所示）而就诊。六个月期间，患者皮疹缓慢进展，从 红色丘疹到水疱状皮疹。


图1左侧胸壁显示以前的乳房切除术手术部位和水疱状皮疹

活检结果显示为乳腺癌皮肤转移。在女性恶性肿瘤中，乳腺癌发现皮肤转移更为常见。它们发生皮肤转移时最常见部位为癌灶同侧胸壁皮肤。

因为就诊时的表现各异而导致乳腺癌皮肤转移的诊断较为困难。转移瘤疱疹样的分布相当罕见，但是乳腺癌皮肤转移患者疱疹样的皮肤表现较为常见。

原始出处：

Ryan Judge, et al. Herpeti form skin metastases.BMJ 2017; http://www.bmj.com/content/357/bmj.j1845

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    2018-01-21 gaoxiaoe

    #BMJ#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1848301, encodeId=993518483012c, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sun Jan 21 02:58:00 CST 2018, time=2018-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1953273, encodeId=ec8219532e3e5, content=<a href='/topic/show?id=bb7be211929' target=_blank style='color:#2F92EE;'>#皮肤转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72119, encryptionId=bb7be211929, topicName=皮肤转移)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Fri Sep 01 10:58:00 CST 2017, time=2017-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=198641, encodeId=5f25198641f0, content=学习了，谢谢分享！, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/29/6902c9c65fe215fc96c6d153c8590e95.JPG, createdBy=f9312054548, createdName=138****1711, createdTime=Tue May 16 06:31:41 CST 2017, time=2017-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580385, encodeId=e0441580385f1, content=<a href='/topic/show?id=c026e05485f' target=_blank style='color:#2F92EE;'>#疱疹#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70548, encryptionId=c026e05485f, topicName=疱疹)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2dcf16628144, createdName=ms2694732865965676, createdTime=Thu May 11 08:58:00 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196078, encodeId=0a531960e8f1, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Wed May 10 07:10:56 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196001, encodeId=86f419600185, content=普通疱疹病毒感染，也可见于嘴唇, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Wed May 10 06:13:03 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=195968, encodeId=7286195968f2, content=非常好的文章，学习了，很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Wed May 10 00:45:11 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=195957, encodeId=2e7019595e5e, content=学习啦，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Wed May 10 00:31:12 CST 2017, time=2017-05-10, status=1, ipAttribution=)]
    2017-09-01 yuanming7

    #皮肤转移#

    0

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    2017-05-16 138****1711

    学习了，谢谢分享！

    0

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    2017-05-11 ms2694732865965676

    #疱疹#

    0

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    2017-05-10 榄枷檬

    谢谢分享

    0

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    2017-05-10 有备才能无患

    普通疱疹病毒感染，也可见于嘴唇

    0

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    2017-05-10 天涯183

    非常好的文章，学习了，很受益

    0

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    2017-05-10 tanxingdoctor

    学习啦，谢谢分享

    0

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Nat Commun：胸部大小与乳腺癌：大胸女性更危险？

胸部大小与乳腺癌的关系——这个“喜闻乐见”的话题一直广受医生和科学家们关注。从1950年开始，关于这一话题的论文已经发表了数百篇，科研界仍莫衷一是。但多数研究认为，胸部大小与乳腺癌发生率和死亡率正相关。2014年，多伦多大学的 M.H.布郎（M.H. Brown）教授和他的同事们在《整形外科与美容外科杂志》（Journal of Plastic， Reconstructive & Ae

JCO：内分泌辅助治疗乳腺癌

研究人员主导的4，724例早期乳腺癌绝经后患者的研究（临床试验资料：ISRCTN11883920）已得出结论。主要研究已经证明，2至3年的他莫昔芬至依西美坦的辅助内分泌治疗与临床相关功效的改善有较大相关度，现在主要报道实验的最终疗效分析。