Neurology:戒酒与急性缺血性卒中预后较差有关

2019-10-27 xing.T MedSci原创

由此可见,AW与费用增加,住院时间更长,AIS后医疗并发症和住院死亡率更高的可能性有关。主动监测和管理AW可能对改善这些患者的预后很重要。

近日,神经病学领域权威取杂志Neurology上发表了一篇研究文章,研究人员旨在明确酗酒(AA)和戒酒(AW)与急性缺血性卒中(AIS)结局之间的关联。 

研究人员从全国住院患者样本中确定了2004年至2014年期间美国因AIS入院的成年病例(n=4438968)。研究人员使用多变量调整模型评估AIS患者AW与住院内并发症、死亡率、成本和住院时间之间的关系。

AA入院的患者为10​​.6%,占所有AIS的0.4%,之后AW。随着时间的流逝,AIS患者中AA和AW的患病率分别增加了45.2%和40.0%(趋势p<0.001)。AA的患者主要为男性(80.2%),白人(65.9%)以及40至59岁(44.6%)和60至79岁(45.6%)年龄组。经过多变量调整后,与无AW的患者相比,AW的AIS入院者尿路感染、肺炎、败血症、肠道出血、深静脉血栓形成和急性肾衰竭的几率增加了50%以上。与没有AW的患者相比,AW的患者在AIS住院期间死亡的可能性也增加32%(比值比为1.32,95%的置信区间为1.11–1.58)。AW与住院时间增加约15天和住院费用增加5000美元(p<0.001)相关。

由此可见,AW与费用增加,住院时间更长,AIS后医疗并发症和住院死亡率更高的可能性有关。主动监测和管理AW可能对改善这些患者的预后很重要。 

原始出处:

Emmanuel O. Akano,et al.Alcohol withdrawal is associated with poorer outcome in acute ischemic stroke.Neurology.2019.https://doi.org/10.1212/WNL.0000000000008518

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    2020-05-17 yinhl1978
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    2019-10-28 yjs木玉

    好好好好好好

    0

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    2019-10-27 qingfengqishi5

    学习了,学习了

    0

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    2019-10-27 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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    2019-10-27 天地飞扬

    有待进一步研究

    0

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