JAMA Intern Med:结肠镜筛查**二氧化碳气腹

2016-06-22 Mechront 译 MedSci原创

“虽然许多美国人经常接受结肠镜筛查,但没有随机试验量化筛选对结直肠癌的发病率和死亡率的影响,”挪威奥斯陆大学经济系健康管理的Michael Bretthauer博士说,“当前发表在JAMA Internal Medicine的NordICC试验,是目前已知的对结肠镜筛查的首次评价,比较了筛查或不筛查对结直肠癌发病率和死亡率的影响。”虽然结直肠癌是高收入国家的第二大癌症,但大多数欧洲国家并没有引入结

“虽然许多美国人经常接受结肠镜筛查,但没有随机试验量化筛选对结直肠癌的发病率和死亡率的影响,”挪威奥斯陆大学经济系健康管理的Michael Bretthauer博士说,“当前发表在JAMA Internal Medicine的NordICC试验,是目前已知的对结肠镜筛查的首次评价,比较了筛查或不筛查对结直肠癌发病率和死亡率的影响。”

虽然结直肠癌是高收入国家的第二大癌症,但大多数欧洲国家并没有引入结肠镜检查的筛查。为了更好的了解这些国家,Bretthauer和同事在挪威,瑞典,波兰和荷兰进行了一项基于人群的结肠镜筛查的随机试验。该试验包括94959名年龄在55至64岁的结直肠癌平均风险的人。研究人员调查了结肠镜筛查的参与率、腺瘤的产量、性能和不良事件。

总体而言,结肠镜筛查的参与率为40%,挪威的参与率为60.7%,瑞典为22.9%,波兰为33%,荷兰为39.8%(P < .001)。盲肠插管率为97.2%,有77.4%没有接受镇静。那些接受结肠镜筛查的参与者中,有一个穿孔(0.01%)、两个息肉浆膜烧伤(0.02%)、18例息肉出血(0.14%)。

在同一组中,62名受试者(0.5%)被诊断为结直肠癌。此外,有30.7%的参与者有腺瘤,其中10.4%被认为是高风险。盲肠插管推荐率(95%)和腺瘤的检出率(25%)与内镜师不符合(17.1%和28.6%),表明不同内镜医师的性能显著不同。此外,标准空气注入技术和co2气腹相比,中度至重度腹痛的患者分别有16.7%和4.2% (P < .001)。

研究者说,“国家和个人之间内镜医师的显著差异还值得进一步的研究,此外结肠镜检查中标准空气注入技术应该放弃,而青睐于co2气腹。”

原始出处:

Bretthauer M, et al. Population-Based Colonoscopy Screening for Colorectal Cancer.JAMA Intern Med. 2016;doi:10.1001/jamainternmed.2016.0960.

Carbon dioxide insufflation preferred over air insufflation in colonoscopy screening.Healio.June 21, 2016

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    2016-09-16 1e10c84am36(暂无匿称)

    不错哦,会学到很多

    0

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    2017-04-01 JR19860227
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    2016-06-24 zhouqu_8
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镇静过程中的合适的检测对患者安全是至关重要的。二氧化碳图可以识别低通气前低氧血症;然而,目前尚不清楚在常规结肠镜检查过程中,加入二氧化碳图能否改善患者安全性或经济效益。。因此研究者进行了一项研究,评估温和镇静的结肠镜检查过程中EtCO2监测的价值。研究者进行了一项前瞻性研究,通过使用经验证的程序式镇静评估调查 (PROSAS)对门诊结肠镜检查患者使用咪达唑仑和芬太尼,探究患者在使用EtCO2监测前

Gastroenterology:麻醉会增加结肠镜检查后并发症风险

近期有研究者对伴或伴麻醉的结肠镜检查进行了一项研究,发表在Gastroenterology的结果称,伴麻醉的结肠镜检查,其后30天内的并发症风险增加13%(与不伴麻醉的结肠镜检查相比)。尤其是穿孔、出血、腹痛、继发于麻醉的相关并发症和卒中风险增加。研究者呼吁,随着无痛结肠镜检查的广泛应用,临床医师和患者应该对其潜在的风险予以重视。该研究共纳入了3,168,228名40-64岁进行结肠镜检查的人群。

Prev Med:婚姻状况也能影响男性的健康行为?单身狗情何以堪..

近期发表在Preventive Medicine的研究称,已婚男性更有可能进行结肠镜筛查,尤其是拥有幸福感爆棚和更高教育的妻子的已婚男性;不过婚姻状况对女性的结肠镜检查率没有影响。芝加哥大学老年病学和姑息医学的主任William Dale博士和同事对3137名成年了进行了研究,其中有804对异性恋夫妇,所有参与者年龄55-90岁。对总样本进行分析后显示,过去5年时间里,对于男性,结肠镜检查率在已婚

Gastrointest Endosc:肠道准备时,少渣饮食优于流质饮食

近期发表在Gastrointest Endosc呃荟萃分析称,结肠镜检查前一天,患者在进食少渣饮食(LRD)后,对重复肠道准备有更好的依从性(与流质饮食(CLD)相比)。此外,患者对低渣饮食的耐受性更好,在不良事件或肠道准备质量方面,两种饮食没有差异。研究者检索Scopus、PubMed/MEDLINE等数据库后,纳入了9项比较结肠镜筛查前一天不同饮食(LRD vs CLD)的随机对照试验进行荟萃