ALZHEIMERS DEMENT:科学家预测阿尔兹海默增长趋势

2017-12-10 海北 MedSci原创

随着全球老龄化的进程,阿尔兹海默病成了社会关注的重点。近日,来自加州大学的研究人员预测了临床前和临床阿尔茨海默病(AD)的患病率,并评估美国一级和二级预防的潜在影响。

随着全球老龄化的进程,阿尔兹海默病成了社会关注的重点。近日,来自加州大学的研究人员预测了临床前和临床阿尔茨海默病(AD)的患病率,并评估美国一级和二级预防的潜在影响。

研究人员使用了一个多国家模式,并结合了临床前AD生物标志物与美国人口预测情况。

研究人员预测,到2017年,美国大约会有608万人后患有临床确诊的阿尔兹海默或是因为阿尔兹海默引起轻度认知障碍。而到2060年,这个数字会增长到1500万。而在2017年,4670万美国人患有临床前阿尔兹海默症状(淀粉样变性,神经退化或两者兼有)。但是许多人在他们的一生中都可能不会发展成临床疾病。研究人员预测,一级和二级预防对未来疾病负担有不同的影响。

鉴于大量人群具有患临床前阿尔兹海默的风险,因此该研究结果强调了对可能发展为临床疾病的人群的二级预防需求,以及无临床前疾病的人群的一级预防需求。


原始出处:

Ron Brookmeyer et al. Forecasting the prevalence of preclinical and clinical Alzheimer's disease in the United States. Alzheimer's & Dementia, 2017; DOI: 10.1016/j.jalz.2017.10.009


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    2018-07-28 anminleiryan
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    2017-12-11 1ddf0692m34(暂无匿称)

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