mSphere:惊人!健康老年人或许拥有着和30岁健康成年人相同功能的肠道微生物组

2017-10-12 佚名 ”细胞“微信号

研究人员发现,健康老年人机体中总体的微生物群落组成和年轻人非常相似,而且在30岁至100多岁之间的人群中其机体中的肠道微生物菌群差比非常小。

近日,来自中国天益健康科学研究院、西安大略大学(加拿大境内)和加拿大罗森健康研究中心的研究人员通过在人类机体中进行大规模的微生物菌群研究,阐明了机体健康老化和肠道健康之间的潜在关联,相关研究刊登于国际杂志mSphere上。

文章中,研究人员对超过1000名中国人机体中的肠道菌群进行研究,这些参与者年龄主要分布在3岁至100多岁多个区段,且没有任何已知的健康问题以及家族疾病史,研究结果表明,参与者的机体健康和其肠道的微生物组之间密切相关。研究者Gregor Reid教授表示,我们的研究目标就是开发出新型的微生物组诊断系统,随后利用食物和益生菌来尝试改善人群机体中的相关生物标志物,那么问题来了,是否我们保持活力、吃得好就能够健康变老?或者说是否通过肠道中的细菌就能够帮助预测个体是否会迎来健康老龄化?

研究人员发现,健康老年人机体中总体的微生物群落组成和年轻人非常相似,而且在30岁至100多岁之间的人群中其机体中的肠道微生物菌群差比非常小。研究者Greg Gloor表示,这篇文章主要的研究结果就是,如果你身体非常健康,且已经90多岁了,那么你机体中肠道微生物群落和一个健康的30多岁成年人并没有什么不同;目前研究人员并不清楚其中所涉及的因果关系,但他们指出,肠道菌群的多样性似乎在他们所研究的参与者中会保持不变。

随着机体老化,维持机体肠道菌群的多样性似乎是我们健康衰老的一个主要的生物标志物,就好像较低水平的胆固醇是机体循环系统保持健康的一个生物标志物一样,研究人员还认为,将老年人群的肠道菌群“重置”为30岁时的状态或许能够帮助促进其机体健康;通过对健康人群进行研究,研究人员希望未来能够改善更多人的健康状况。

此外,研究者还在19-24岁的人群中的肠道菌群中发现了一种明显异常的状况,而这些异常在对其它人群的大规模分析中并未观察到,他们推测,这或许是对中国健康人群而言独一无二的。19-24岁人群机体中明显不同的肠道菌群似乎应该值得关注,而研究人员表示后期也会对此进行更为深入的研究。

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    2017-10-24 虈亣靌

    一起学习吧.很好的资源

    0

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    2017-10-15 虈亣靌

    学习了.获益匪浅!感谢分享

    0

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    2017-10-13 yunger

    很好的专题,值得品味及分享

    0

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    2017-10-13 1dd8c52fm63(暂无匿称)

    学习学习.继续关注

    0

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    2017-10-12 hhh678

    henhao

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    2017-10-12 衣带渐宽

    学习

    0

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