Colorectal Dis:直肠癌前切除术肠系膜下动脉高位结扎与术后功能异常

2017-11-27 zhangfan MedSci原创

研究认为,直肠癌前切除术时肠系膜下动脉高位结扎与术后2年的患者大小便以及性功能异常不相关

观察性研究发现直肠癌前切除术时肠系膜下动脉高位结扎可能与术后功能紊乱风险增加有关。近日研究人员开展人群队列回顾性研究考察二者的相关性。

研究在瑞典开展,2011-12年间进行直肠癌前切除术患者参与,术后2年进行肠道和泌尿生殖功能问卷评估。调整如性别、体重指数、合并症和术前放疗等混杂因素后,采用多变量逻辑回归和线性回归分析考察高位结扎与功能异常之间的关系。

问卷回访率为86%,805名患者参与研究,其中46%的患者进行高位结扎。多因素调整后,高位结扎与大便失禁(OR 0.85; 95% CI 0.59–1.22)、尿失禁(OR 0.94; 95% CI 0.63–1.41)以及性功能障碍(勃起功能障碍、不射精、性交疼痛、性交阴道干燥)不相关,高位结扎患者会出现夜间排便现象(OR 1.44; 95% CI 1.02–2.03)。

研究认为,直肠癌前切除术时肠系膜下动脉高位结扎与术后2年的患者大小便以及性功能异常不相关。

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    2018-04-04 zhouqu_8
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    2018-09-15 windight
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    2017-11-29 zzc2216