Sci Rep:全身性动脉高压能够导致精子质量下降和改变睾丸微循环

2019-08-16 AlexYang MedSci原创

动脉高压是一种心血管疾病,能够引起重要的系统性改变并对正常的器官功能造成巨大的损伤。高血压大约影响了大约7亿处于生殖年龄的男性,并且高血压男性还表现出了生殖障碍风险的增加,比如阴茎勃起功能障碍。然而,动脉高血压与男性生殖障碍可能是有联系的。更多的是,许多研究已经报道了男性生殖力下降/精子质量下降和男性健康改变。最近,有研究人员调查了全身性高血压对精子质量、精子功能特性和睾丸生理情况。研究发现,在小

动脉高压是一种心血管疾病,能够引起重要的系统性改变并对正常的器官功能造成巨大的损伤。高血压大约影响了大约7亿处于生殖年龄的男性,并且高血压男性还表现出了生殖障碍风险的增加,比如阴茎勃起功能障碍。然而,动脉高血压与男性生殖障碍可能是有联系的。更多的是,许多研究已经报道了男性生殖力下降/精子质量下降和男性健康改变。

最近,有研究人员调查了全身性高血压对精子质量、精子功能特性和睾丸生理情况。研究发现,在小鼠模型中高血压小鼠的睾丸形态发生了改变,主要是血管改变和睾丸血管收缩受损。高血压小鼠同时也表现出了精子浓度的减少、DNA完整度的减少,并且线粒体功能和细胞内超氧阴离子活性异常以及形态异常的精子比例增加。

最后,研究人员指出,他们的结果阐释了高血压影响睾丸的相关机制,证明了高血压能够对睾丸产生影响并影响精子质量。

原始出处:

Lucas Giglio Colli, Larissa Berloffa Belardin, Cinthya Echem et al. Systemic arterial hypertension leads to decreased semen quality and alterations in the testicular microcirculation in rats. Sci Rep. 30 Jul 2019

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    2019-08-18 zhangph
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    2019-08-17 最帅小男护

    不错

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