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Circulation子刊：抑郁会增加稳定型心绞痛患者的死亡风险

2016-10-05 Mechront 译 MedSci原创

稳定型心绞痛抑郁死亡
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近期有数据显示，对于稳定型心绞痛患者，稳定型心绞痛患者了患者的全因死亡率和心肌梗死的风险。 虽然心肌梗死后抑郁十分常见，但是关于抑郁和稳定型心绞痛之间的关系知之甚少。来自多伦多大学的Natalie Szpakowski博士称，抑郁症会影响近五分之一的稳定型心绞痛患者，且与死亡或心肌梗死等较差预后有关。 他们对22917例≥20岁的稳定型心绞痛患者进行了回顾性研究，所有诊断均是基于血管造

近期有数据显示，对于稳定型心绞痛患者，稳定型心绞痛患者了患者的全因死亡率和心肌梗死的风险。

虽然心肌梗死后抑郁十分常见，但是关于抑郁和稳定型心绞痛之间的关系知之甚少。来自多伦多大学的Natalie Szpakowski博士称，抑郁症会影响近五分之一的稳定型心绞痛患者，且与死亡或心肌梗死等较差预后有关。

他们对22917例≥20岁的稳定型心绞痛患者进行了回顾性研究，所有诊断均是基于血管造影发现阻塞性CAD，以探究这类患者的抑郁情况。

主要终点为全因死亡率。次要终点为心肌梗死入院或血运重建。

在最初的队列中，12.7%的患者因为新近诊断为抑郁症，而被被排除在外；在最终的队列中，有31.1%的患者诊断为抑郁症。

在最终的队列中，18.8%的患者（n = 4305）在血管造影后首次出现抑郁症（平均随访1084天；发生率63.2/1000人年）。

相比那些没有抑郁症的患者，抑郁症患者的全因死亡率风险更高(HR = 1.83; 95% CI, 1.62-2.07)、心肌梗死入院风险更高(HR = 1.36, 95% CI, 1.1-1.67)。

不过不同抑郁状态患者的血运重建方面没有差异(HR = 1.13; 95% CI, 0.99-1.28)。

原始出处：

Depression linked to adverse outcomes in patients with stable angina.Healio.October 4, 2016

Szpakowski N, et al. Clinical Impact of Subsequent Depression in Patients With a New Diagnosis of Stable Angina.Circ Cardiovasc Qual Outcomes. 2016;doi:10.1161/CIRCOUTCOMES.116.002904.

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    2017-09-07 108807375_62823127

    #稳定型#

    0

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    2016-10-14 1e0ece0dm09(暂无匿称)

    谢谢指点学习

    0

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    2016-10-12 1e10c84am36(暂无匿称)

    好文章，受益

    0

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    2016-10-11 1e10c84am36(暂无匿称)

    好文章，受益

    0

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    2016-10-07 quxin068

    #死亡风险#

    0

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    2016-10-07 lizhou0209

    #稳定型心绞痛#

    0

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    2016-10-05 明月清辉

    A型性格的人会增加冠心病的发病率。

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1803347, encodeId=628d180334e73, content=<a href='/topic/show?id=8b44e528972' target=_blank style='color:#2F92EE;'>#稳定型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75289, encryptionId=8b44e528972, topicName=稳定型)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18b32500069, createdName=108807375_62823127, createdTime=Thu Sep 07 08:57:00 CST 2017, time=2017-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148281, encodeId=252c148281e6, content=谢谢指点学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Fri Oct 14 21:17:23 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=146369, encodeId=9d9f14636947, content=好文章，受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Oct 12 09:40:10 CST 2016, time=2016-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=145493, encodeId=a7931454931d, content=好文章，受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Oct 11 20:25:27 CST 2016, time=2016-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255595, encodeId=fec112555956c, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Fri Oct 07 05:57:00 CST 2016, time=2016-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1568887, encodeId=58b0156888e5b, content=<a href='/topic/show?id=7de4e529403' target=_blank style='color:#2F92EE;'>#稳定型心绞痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75294, encryptionId=7de4e529403, topicName=稳定型心绞痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=615115475291, createdName=lizhou0209, createdTime=Fri Oct 07 05:57:00 CST 2016, time=2016-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140417, encodeId=9e7c14041e5d, content=A型性格的人会增加冠心病的发病率。, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Wed Oct 05 15:43:46 CST 2016, time=2016-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140396, encodeId=7d3b140396f7, content=真的嘛？？继续关注与学习！, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Wed Oct 05 15:14:36 CST 2016, time=2016-10-05, status=1, ipAttribution=)]
    2016-10-05 榄枷檬

    真的嘛？？继续关注与学习！

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