Nat Commun:嚼嚼口香糖,就能诊断种植牙是否发炎的技术离我们不远了

2017-08-16 佚名 Nature自然科研

本周《自然-通讯》发表的一项研究Diagnosing peri-implant disease using the tongue as a 24/7 detector介绍了一种具有诊断功能的口香糖,它可以检测由牙种植体引发的炎症。这种简单的诊断方法“任何人任何地点任何时间”都能使用,或有助于简化种植体周围病的诊断。

本周《自然-通讯》发表的一项研究Diagnosing peri-implant disease using the tongue as a 24/7 detector介绍了一种具有诊断功能的口香糖,它可以检测由牙种植体引发的炎症。这种简单的诊断方法“任何人任何地点任何时间”都能使用,或有助于简化种植体周围病的诊断。

“任何人任何地点任何时间”的目标是通过免除临床检测的需要,提高医学诊断的可获取性。这种方法依赖易于识别却不易误读的信号来确诊。

图片:Pixabay

德国维尔茨堡大学的Lorenz Meinel及同事开发了一种生物传感器来检测种植体周围病,产生苦味则标志着阳性诊断。他们将传感器与一种复合物结合在一起,然后再将其嵌入口香糖中——对于健康者来说是无味的。但是,如果患有种植体周围病,则会增加特定酶的生成,使生物传感器打开,将具有强烈苦味的复合物释放出来。研究小组在研究中采用了“人造舌头”,通过检测苦味复合物,它可以将患有种植体周围病患者的唾液样本和无症状志愿者的区别开来。


生物传感器及其工作原理。Ritzer et al.

虽然还没有在临床环境下在志愿者身上进行测试,但是可以说,这种口香糖有望免去诊断阶段的复杂试剂和专家干预需要。作者表示,未来某一天,这种口香糖可能就会出现在牙医诊所里,或者为个人所用。

原始出处:J. Ritzer, T. Lühmann, C. Rode, et al. Diagnosing peri-implant disease using the tongue as a 24/7 detector. Nat Commun 8.

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    2018-06-10 liye789132251
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    2017-10-11 huangdf
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    2017-08-17 lyh994

    如果患有种植体周围病,则会增加特定酶的生成,使生物传感器打开,将具有强烈苦味的复合物释放出来。

    0

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