Clinica Chimica Acta:基于非酯化脂肪酸不平衡的血清白蛋白饱和试验

2019-09-22 gladiator MedSci原创

脂肪酸是人体细胞的基本能量和结构来源。它们通常不会在人体循环中自由存在。

脂肪酸是人体细胞的基本能量和结构来源。它们通常不会在人体循环中自由存在。脂肪酸代谢的改变与糖尿病、子痫前期、心脏病和一些传染病有关。非酯化脂肪酸(NEFA)水平升高可能导致细胞功能障碍和脂肪毒性。由于生理脂肪酸是与白蛋白结合运输的,我们在此提出一种简单而廉价的测试方法,包括白蛋白等电聚焦测定,以测量潜在的系统NEFA细胞毒性。

为验证该方法的有效性,对40例危重病人和11例对照者的51份血清样本进行白蛋白等电聚焦,并与高效液相色谱法测定的NEFA/白蛋白比值进行比较。我们称这种方法为白蛋白饱和度测试。这项测试可能向医生表明潜在的NEFA脂肪毒性,指导他们更好地管理病人。白蛋白饱和度测试可以通过一种廉价的检测方法来指出血清白蛋白NEFA的饱和度,这种检测方法可以在任何护理机构进行。

原始出处:

Cassiano Felippe Gonçalves-de-AlbuquerqueMarcos Roberto Colombo BarneseSerum albumin saturation test based on non-esterified fatty acids imbalance for clinical employment

本文系梅斯医学(MedSci)原创编译整理,转载需授权!


版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (3)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1849750, encodeId=6e611849e505e, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Wed May 13 08:07:00 CST 2020, time=2020-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1304662, encodeId=622b1304662a5, content=<a href='/topic/show?id=cd37e1767b5' target=_blank style='color:#2F92EE;'>#白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71767, encryptionId=cd37e1767b5, topicName=白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25d7319, createdName=珙桐, createdTime=Tue Sep 24 08:07:00 CST 2019, time=2019-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585048, encodeId=84721585048f0, content=<a href='/topic/show?id=9ec189429de' target=_blank style='color:#2F92EE;'>#血清白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89429, encryptionId=9ec189429de, topicName=血清白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=41b317108500, createdName=lifestar, createdTime=Tue Sep 24 08:07:00 CST 2019, time=2019-09-24, status=1, ipAttribution=)]
    2020-05-13 windight
  2. [GetPortalCommentsPageByObjectIdResponse(id=1849750, encodeId=6e611849e505e, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Wed May 13 08:07:00 CST 2020, time=2020-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1304662, encodeId=622b1304662a5, content=<a href='/topic/show?id=cd37e1767b5' target=_blank style='color:#2F92EE;'>#白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71767, encryptionId=cd37e1767b5, topicName=白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25d7319, createdName=珙桐, createdTime=Tue Sep 24 08:07:00 CST 2019, time=2019-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585048, encodeId=84721585048f0, content=<a href='/topic/show?id=9ec189429de' target=_blank style='color:#2F92EE;'>#血清白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89429, encryptionId=9ec189429de, topicName=血清白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=41b317108500, createdName=lifestar, createdTime=Tue Sep 24 08:07:00 CST 2019, time=2019-09-24, status=1, ipAttribution=)]
    2019-09-24 珙桐
  3. [GetPortalCommentsPageByObjectIdResponse(id=1849750, encodeId=6e611849e505e, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Wed May 13 08:07:00 CST 2020, time=2020-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1304662, encodeId=622b1304662a5, content=<a href='/topic/show?id=cd37e1767b5' target=_blank style='color:#2F92EE;'>#白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71767, encryptionId=cd37e1767b5, topicName=白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25d7319, createdName=珙桐, createdTime=Tue Sep 24 08:07:00 CST 2019, time=2019-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585048, encodeId=84721585048f0, content=<a href='/topic/show?id=9ec189429de' target=_blank style='color:#2F92EE;'>#血清白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89429, encryptionId=9ec189429de, topicName=血清白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=41b317108500, createdName=lifestar, createdTime=Tue Sep 24 08:07:00 CST 2019, time=2019-09-24, status=1, ipAttribution=)]