移植物抗宿主病治疗的新契机:FDA批准Jakafi用于类固醇难治性急性GVHD

2019-05-25 不详 网络

Incyte近日宣布,FDA已经批准Jakafi(ruxolitinib)用于治疗类固醇难治性急性移植物抗宿主病(GVHD)的12岁及以上的患者。Incyte首席执行官HervéHoppenot表示:“这是针对类固醇难治性急性GVHD的患者的首款获批药物”。

Incyte近日宣布,FDA已经批准Jakafiruxolitinib)用于治疗类固醇难治性急性移植物抗宿主病(GVHD)的12岁及以上的患者。Incyte首席执行官HervéHoppenot表示:这是针对类固醇难治性急性GVHD的患者的首款获批药物

这一批准得到了IIREACH1试验的数据支持,该试验评估了71名患有类固醇难治性II-IV级急性GVHD患者,在试验中,对这些患者采取了Jakafi联合皮质类固醇激素的治疗。去年6月公布的最佳结果显示,该研究已达到其主要终点:28天治疗后总体反应率为55%。


原始出处:

http://www.firstwordpharma.com/node/1643100#axzz5ovUpnHnX

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    2020-04-05 xuyong535
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    2019-05-27 wincls
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    2019-05-27 freve
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