J Mech Behav Biomed Mater:钛纤维增强生物活性玻璃支架的生物机械性能如何

2018-01-22 MedSci MedSci原创

尽管用生物活性玻璃所制备的植体在骨修复方面显示出巨大应用前景,但是其机械性能较人骨差,故其在修复承重长骨方面的应用受到限制。本研究旨在探究低温挤压自由成形技术制造的钛(Ti)纤维增强生物活性硅酸盐13-93玻璃支架的生物及机械性能。使用13-93玻璃和Ti纤维(直径〜16μm,长度从〜200μm到〜2mm)制备的复合糊料通过喷嘴挤出以在加热板上制造支架(0-90°长丝定向图案)。烧结的支架测量的孔

尽管用生物活性玻璃所制备的植体在骨修复方面显示出巨大应用前景,但是其机械性能较人骨差,故其在修复承重长骨方面的应用受到限制。本研究旨在探究低温挤压自由成形技术制造的钛(Ti)纤维增强生物活性硅酸盐13-93玻璃支架的生物及机械性能。

使用13-93玻璃和Ti纤维(直径〜16μm,长度从〜200μm到〜2mm)制备的复合糊料通过喷嘴挤出以在加热板上制造支架(0-90°长丝定向图案)。烧结的支架测量的孔径范围为400-800μm,孔隙率为〜50%。0.4vol%Ti纤维支架材料断裂韧性约为~0.8MPam1/2,弯曲强度约为~15MPa。

没有Ti纤维的13-93玻璃支架的韧性约为~0.5MPam1/2,强度约为~10MPa。Ti纤维的添加使支架的断裂韧性提高了〜70%,弯曲强度提高了〜40%。通过将支架浸入模拟体液中1至4周,评估支架的生物相容性及其在体外机械性能中的降解。

原始出处:

Thomas A, Kolan KCR, Leu MC1, Hilmas GE. Freeform extrusion fabrication of titanium fiber reinforced 13-93 bioactive glass scaffolds. J Mech Behav Biomed Mater. 2017 Jun;70:43-52. doi: 10.1016/j.jmbbm.2016.12.025.

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    2018-03-20 sunylz
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    2018-04-05 30397613
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    2018-01-24 qjddjq
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