Brit J Surg:青年结直肠癌患者数量有所增加!

2017-06-26 xing.T MedSci原创

由此可见,在实施筛查策略时,需要考虑年轻患者直肠癌发病率有所增加。

新西兰是世界上结直肠癌发病率最高的国家之一。近日,外科疾病领域权威杂志British Journal of Surgery上发表了一篇研究文章,该研究的目的是确定新西兰人群在引入全国结直肠癌筛查前肿瘤发病率和肿瘤部位的变化趋势。

研究所用数据来自于国家癌症登记中心,与1995年至2012年期间的人口数据相互链接。研究人员通过线性回归分析评估了根据性别、年龄(小于50岁,50-79岁,80岁以上)和位置(近端结肠、远端结肠和直肠)的结直肠癌发病率。

在50岁以下的患者中,男性中远端结肠肿瘤的发生率每十年增加了14%(发病率比值(IRR为1.14),95%可信区间为1.00-1.30;P=0.042);男性中直肠癌症的发病率增加了18%(IRR为1.18, 1.06-1.32;P=0.002),女性增加了13%(IRR为1.13, 1.02-1.26;P=0.023)。在那些50-79岁的受试者中,每十年男性和女性近端结肠、远端结肠和直肠癌的发生率有所降低。在80岁及以上受试者中,女性近端结肠癌发病率每十年增加了19%(IRR为1.19, 1.13-1.26;P<0.001)以及在男性中增加了25%(IRR为1.25, 1.18-1.32;P<0.001);在女性中,远端结肠癌发病率下降了8%(IRR为0.92, 0.86-0.98;P=0.012),直肠癌也是一样的(IRR为0.92, 0.86-0.97;P=0.005)。

由此可见,在实施筛查策略时,需要考虑年轻患者直肠癌发病率有所增加。

原始出处:


J. Gandhi,et al. Population-based study demonstrating an increase in colorectal cancer in young patients. British Journal of Surgery.2017. http://onlinelibrary.wiley.com/doi/10.1002/bjs.10518/full

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=217305, encodeId=b4b921e3050d, content=学习并分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sat Jul 01 09:27:53 CST 2017, time=2017-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452927, encodeId=817c145292ed6, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Wed Jun 28 07:43:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215979, encodeId=16792159e97b, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=550d2008262, createdName=luominglian113, createdTime=Tue Jun 27 13:35:37 CST 2017, time=2017-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215662, encodeId=763f21566265, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Mon Jun 26 17:48:31 CST 2017, time=2017-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215652, encodeId=b8d5215652a5, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Mon Jun 26 17:12:31 CST 2017, time=2017-06-26, status=1, ipAttribution=)]
    2017-07-01 大爰

    学习并分享!!

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=217305, encodeId=b4b921e3050d, content=学习并分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sat Jul 01 09:27:53 CST 2017, time=2017-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452927, encodeId=817c145292ed6, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Wed Jun 28 07:43:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215979, encodeId=16792159e97b, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=550d2008262, createdName=luominglian113, createdTime=Tue Jun 27 13:35:37 CST 2017, time=2017-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215662, encodeId=763f21566265, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Mon Jun 26 17:48:31 CST 2017, time=2017-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215652, encodeId=b8d5215652a5, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Mon Jun 26 17:12:31 CST 2017, time=2017-06-26, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=217305, encodeId=b4b921e3050d, content=学习并分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sat Jul 01 09:27:53 CST 2017, time=2017-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452927, encodeId=817c145292ed6, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Wed Jun 28 07:43:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215979, encodeId=16792159e97b, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=550d2008262, createdName=luominglian113, createdTime=Tue Jun 27 13:35:37 CST 2017, time=2017-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215662, encodeId=763f21566265, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Mon Jun 26 17:48:31 CST 2017, time=2017-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215652, encodeId=b8d5215652a5, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Mon Jun 26 17:12:31 CST 2017, time=2017-06-26, status=1, ipAttribution=)]
    2017-06-27 luominglian113

    学习了,谢谢分享

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=217305, encodeId=b4b921e3050d, content=学习并分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sat Jul 01 09:27:53 CST 2017, time=2017-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452927, encodeId=817c145292ed6, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Wed Jun 28 07:43:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215979, encodeId=16792159e97b, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=550d2008262, createdName=luominglian113, createdTime=Tue Jun 27 13:35:37 CST 2017, time=2017-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215662, encodeId=763f21566265, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Mon Jun 26 17:48:31 CST 2017, time=2017-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215652, encodeId=b8d5215652a5, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Mon Jun 26 17:12:31 CST 2017, time=2017-06-26, status=1, ipAttribution=)]
    2017-06-26 dhzzm

    学习了分享了

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=217305, encodeId=b4b921e3050d, content=学习并分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sat Jul 01 09:27:53 CST 2017, time=2017-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452927, encodeId=817c145292ed6, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Wed Jun 28 07:43:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215979, encodeId=16792159e97b, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=550d2008262, createdName=luominglian113, createdTime=Tue Jun 27 13:35:37 CST 2017, time=2017-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215662, encodeId=763f21566265, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Mon Jun 26 17:48:31 CST 2017, time=2017-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215652, encodeId=b8d5215652a5, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Mon Jun 26 17:12:31 CST 2017, time=2017-06-26, status=1, ipAttribution=)]
    2017-06-26 三生有幸9135

    学习一下谢谢分享

    0

相关资讯

青年医生该如何打造个人品牌?

有人认为,医生品牌的建立包括两个方面,一方面是自身实力的提升;另一方面是在专业本身以外是否做出与众不同的成绩。 在医生多点执业逐渐成为业内共识,医生个人品牌的建立显得越发重要的大背景下,一群有识之士在北京搭起了一个汇聚媒体界、医疗界的权威大咖和后起之秀的平台,让各界分享与探讨医生成长路径中的品牌构建问题。 11月26日,感恩节,北京大学肿瘤医院国际诊疗中心·北京新里程肿瘤医院主办的“感恩&

SCI REP:健康青少年DNA甲基化与端粒长度的关系分析!

这项研究首次表明低水平的DNA甲基化与年轻人端粒长度的减少相关,这可能会降低基因组的稳定性并增加疾病的易感性。需要进一步的纵向研究来明确整体DNA甲基化随着时间推移对LTL保持的影响。

JAHA:年轻人要警惕卒中和TIA

背景:研究报告称,年轻成人缺血性脑卒中的发病率高于50岁至55岁的成年人。对其他亚型的卒中和短暂性脑缺血发作(TIA)的时间趋势信息是不足的。本研究的目的是探讨年龄15岁至30岁TIA和卒中住院率的变化趋势,包括性别和亚型特异性趋势。方法和结果:从丹麦国家病人登记记录中,研究者确定在丹麦所有1994-2012年住院的首次卒中和TIA患者(年龄15-30岁)。采用泊松回归估计估计年度百分比变化率(E

Circulation:178962名青年癌症患者五年内出现脑血管事件的风险

中枢神经系统肿瘤、头颈部肿瘤和白血病患者因脑血管事件住院的风险尤其高。

2015NICE指南——儿童和青年人糖尿病(1型和2型)的诊断和管理(NG.18)发布

2015年8月,英国国家卫生与临床优化研究所 (NICE)发布了儿童和青年人糖尿病(1型和2型)的诊断和管理指南。该指南更新并替代了NICE儿童和青少年1型糖尿病指南(CG15)。全文获取:下载地址:指南下载(需要扣积分2分, 梅斯医学APP免积分下载) 

Sleep:青年人晚睡1小时,BMI增加2.1kg/m2

对许多人来说,处于青春期和成年初期的人们经常熬夜并参加各种派对。研究表明,如果民众晚睡和熬夜的话会导致他们的体重增加。 发表在Sleep的的新近研究表明,青少年或年轻人如果平时晚睡,则增重的风险增加。这项研究是由加利福尼亚伯克利分校的Lauren Asarnow和来自哥伦比亚大学的同事联合完成。它是第一个评估各个时间段民众睡眠时间和BMI关系的观察性研究。根据国家睡眠协会的建议,14-17岁的青少