J ALZHEIMERS DIS:利用机器学习对认知障碍进行诊断未来能够成为可能么?

2017-05-20 MedSci MedSci原创

对于痴呆症的早期诊断具有重要的临床和社会意义。最近使用对话分析(CA)定性方法的研究表明,语言和沟通问题在患者和神经学家之间是非常明显的,而基于对此的观察可以用来区分认知障碍是由于神经退行性疾病(ND)还是功能性的记忆障碍(FMD)所导致的。

近日,JOURNAL OF ALZHEIMERS DISEASE在线发表了一项关于记忆力减退诊断对话分析自动化的研究,探讨了利用机器学习对认知障碍进行诊断是否可以实现自动化。

对于痴呆症的早期诊断具有重要的临床和社会意义。最近使用对话分析(CA)定性方法的研究表明,语言和沟通问题在患者和神经学家之间是非常明显的,而基于对此的观察可以用来区分认知障碍是由于神经退行性疾病(ND)还是功能性的记忆障碍(FMD)所导致的。 

本研究探讨了记忆诊所中医患相互作用的差异诊断分析是否可以自动化。方法:手动逐字记录神经病学家和最初出现记忆障碍的患者之间对话(FMD15份,ND15份)。一系列自动检测的特征,包含声学,词汇,语义和视觉信息用于复制诊断定性观察。这些特征被用于训练一套五种分类的机器学习,以区分NDFMD

研究结果显示,NDFMD正确分类的平均值为93%,包括由感知分类器的97%到随机森林分类器的90%。使用十个最佳特征值,平均正确分类得分可提高到95%。

这项试点研究提供机器学习方法分析神经病学家和描述记忆问题的患者之间的相互作用的记录的原理证明,并可以将神经退行性与功能性的记忆障碍的患者区分开来。

原始出处:

Mirheidari, Bahmana, Blackburn, Danielb, Harkness, Kirsty, et al. Toward the Automation of Diagnostic Conversation Analysis in Patients with Memory Complaints.

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    2017-11-24 anminleiryan
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1779757, encodeId=195e1e79757ff, content=<a href='/topic/show?id=51b4238909' target=_blank style='color:#2F92EE;'>#alzheimers#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2389, encryptionId=51b4238909, topicName=alzheimers)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=930e243, createdName=dingxiaobo, createdTime=Fri Oct 13 01:44:00 CST 2017, time=2017-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2012254, encodeId=0dc3201225402, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Dec 05 12:44:00 CST 2017, time=2017-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1878207, encodeId=86a918e820797, content=<a href='/topic/show?id=c157696175' target=_blank style='color:#2F92EE;'>#ERS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6961, encryptionId=c157696175, topicName=ERS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e93e105, createdName=anminleiryan, createdTime=Fri Nov 24 19:44:00 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1338456, encodeId=c812133845652, content=<a href='/topic/show?id=767711566a9' target=_blank style='color:#2F92EE;'>#MERS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11566, encryptionId=767711566a9, topicName=MERS)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/71tKRib0PibveVjnEa7tPLMaCzoKicFlKSEOzRTGf4wNvDV54kJyNx1ott1D5Xp5gRu7IwUia77oN0YFdffvQMu6Ug/132, createdBy=9e302500146, createdName=ms49895894946433513521, createdTime=Mon May 22 05:44:00 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1583022, encodeId=f34d158302274, content=<a href='/topic/show?id=f6e1611840d' target=_blank style='color:#2F92EE;'>#机器#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61184, encryptionId=f6e1611840d, topicName=机器)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=13dc16973127, createdName=ms6279672939590805, createdTime=Mon May 22 05:44:00 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200821, encodeId=81ff200821fa, content=人工智能,在未来会应用越来越广~, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Sun May 21 11:16:17 CST 2017, time=2017-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200814, encodeId=830820081469, content=未来的人工智能不知会强大到何种程度, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/24/1c2dbd6706e64df33befd6663f1d6b37.jpg, createdBy=94f61661779, createdName=lyh994, createdTime=Sun May 21 10:53:03 CST 2017, time=2017-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200668, encodeId=3b24200668d8, content=先进, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sun May 21 06:42:38 CST 2017, time=2017-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200467, encodeId=f59e20046e62, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Sat May 20 16:00:44 CST 2017, time=2017-05-20, status=1, ipAttribution=)]
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    2017-05-21 Lisa971

    人工智能,在未来会应用越来越广~

    0

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    2017-05-21 lyh994

    未来的人工智能不知会强大到何种程度

    0

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    2017-05-21 meiliwuxian

    先进

    0

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    2017-05-20 三生有幸9135

    学习一下谢谢分享

    0

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