Diabetes Care:糖尿病早期干预可减少高血糖症和医院获得性感染

2019-04-03 xing.T 网络

由此可见,早期识别和管理糖尿病住院患者可降低高血糖和医院获得性感染。

近日,糖尿病领域权威杂志Diabetes Care上发表了一篇研究文章,研究人员旨在调查糖尿病住院患者的早期电子识别和床边管理是否可以改善非重症疾病患者的血糖控制。

研究人员对一种主动或早期干预护理模式(其中住院糖尿病团队通过电子方式识别患有糖尿病的个体,旨在在入院后24小时内提供床边管理)与常规护理(转诊咨询服务)相比较,并对8个病区进行了一项集群随机试验,包括10周的基线期(所有集群接受常规护理),然后是12周的活动期(随机分组到早期干预或常规护理)。结局为不良血糖天数(AGD)(葡萄糖<4或>15mmol/L [<72或>270mg/dL]的患者天数)和不良患者预后。

研究人员纳入了1002名连续成年住院的糖尿病或新发糖尿病患者。通过早期干预,更多患者接受了专科糖尿病治疗(92% vs. 15%,P<0.001)和新近胰岛素治疗(57% vs. 34%,P=0.001)。在集群水平,AGD的发生率从干预组中的每日1000名患者中的243人降至186人,减少了24%(P<0.001),对照组无变化。在个体水平上,干预组调整后的人均AGD数从平均1.4(SD为1.6)降至1.0(0.9)天(变化了-28%[95%CI为-45至-11%],P=0.001),但在对照组中没有变化(1.8[2.0]降至1.5[1.8],变化了-9%[-25至6%],P=0.23)。早期干预可明显减少高血糖症(平均血糖>15mmol/L的患者天数减少55%,P<0.001)和医院获得性感染(比值比为0.20[95%CI为0.07-0.58],P=0.003)。

由此可见,早期识别和管理糖尿病住院患者可降低高血糖和医院获得性感染

原始出处:

Mervyn Kyi,et al.Early Intervention for Diabetes in Medical and Surgical Inpatients Decreases Hyperglycemia and Hospital-Acquired Infections: A Cluster Randomized Trial.Diabetes Care.2019.https://doi.org/10.2337/dc18-2342

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    2019-12-11 智慧医人
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    2019-04-04 hbwxf
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    2019-04-03 misszhang

    谢谢MedSci提供最新的资讯

    0