JAMA Otolaryngol Head Neck Surg:突发神经性听力损失的高压氧治疗和药物治疗比较

2019-07-05 AlexYang MedSci原创

突发神经性听力损失(SSNHL)在72小时内发生,并且在3个或者更多的连续频率中至少为30dB。尽管类固醇治疗是有益的,但仍旧需要额外的治疗。最近,一些系统性的回顾评估了在SSNHL患者中高压氧治疗(HBO)与恢复效果之间的相关性。研究指出,这些系统性的回顾阐释了HBO可能为传统的皮质类固醇等药物治疗方法提供额外的治疗价值,尤其是在那些具有重度听力损失的案例。使用皮质类固醇(全身和/或非典型性)

突发神经性听力损失(SSNHL)在72小时内发生,并且在3个或者更多的连续频率中至少为30dB。尽管类固醇治疗是有益的,但仍旧需要额外的治疗。最近,一些系统性的回顾评估了在SSNHL患者中高压氧治疗(HBO)与恢复效果之间的相关性。

研究指出,这些系统性的回顾阐释了HBO可能为传统的皮质类固醇等药物治疗方法提供额外的治疗价值,尤其是在那些具有重度听力损失的案例。使用皮质类固醇(全身和/或非典型性) 的药物治疗被定义为的标准治疗,如果适用,还可与其他药物(如抗病毒或血管扩张剂治疗)组合使用。结果与预期的一样,因为那些患者在临床背景下恢复较差,但能够获得较大的绝对益处。然而,这些研究的方法学质量却并不好,偏倚的风险高。更多的是,结果的测量在不同的研究之间差异较大,导致了比较研究和混样研究的困难。

最后,研究人员认为,高压氧治疗的推荐度较低。

原始出处:

Ahmed B. Bayoumy,Erwin Lammet van der Veen,Jacob Alexander de Ru. Hyperbaric Oxygen Therapy vs Medical Therapy for Sudden Sensorineural Hearing Loss. JAMA Otolaryngol Head Neck Surg. 20 Jun 2019

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    2020-04-06 智慧医人
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    2019-07-07 ysjykql
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    2019-07-05 329523732

    不错

    0

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