J Indian Soc Periodontol:吸烟者中核因子κB-β受体激动剂与临床附着水平的关系

2018-03-03 MedSci MedSci原创

牙周炎患者中,与健康同龄人相比,核因子κ-β配体受体激活剂即RANKL的水平较高。本研究旨在测量水烟吸入者中RANKL的唾液水平,并找出RANKL唾液水平与临床牙周参数之间的可能相关性。 研究共纳入了89名(49名水烟吸烟者和40名不吸烟者)参与者。使用人RANKL酶联免疫吸附测定试剂盒收集整个未刺激的唾液样品以定量测定RNAKL。记录每名参与者的菌斑指数、牙龈指数、探诊时出血、牙周袋深度(PPD

牙周炎患者中,与健康同龄人相比,核因子κ-β配体受体激活剂即RANKL的水平较高。本研究旨在测量水烟吸入者中RANKL的唾液水平,并找出RANKL唾液水平与临床牙周参数之间的可能相关性。

研究共纳入了89名(49名水烟吸烟者和40名不吸烟者)参与者。使用人RANKL酶联免疫吸附测定试剂盒收集整个未刺激的唾液样品以定量测定RNAKL。记录每名参与者的菌斑指数、牙龈指数、探诊时出血、牙周袋深度(PPD)和临床附着水平(CAL)。使用曼-惠特尼U检验来检测组间任何差异,P <0.05。Spearman相关系数检验用于检验变量之间的关联。线性回归用于调查相关变量之间的因果关系。

结果显示,RANKL,PPD和CAL显示水烟吸烟者和非吸烟者之间存在统计学差异(P <0.05)。发现RANKL与CAL呈正相关,在本研究样本中约有62.8%的CAL可由RANKL解释。回归方程为CAL = 1.744 + 0.004(RANKL)。

综上所述,该研究结果表明,RANKL的唾液水平与CAL呈正相关。

原始出处:

Al-Mufti SMT, Saliem SS, Abdulbaqi HR. The association between receptor activator of nuclear factor kappa-β ligand and clinical attachment level among waterpipe smoker. J Indian Soc Periodontol. 2017 Sep-Oct;21(5):376-379. doi: 10.4103/jisp.jisp_124_17.

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    2018-03-05 xiaogang319
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    2018-03-03 1e0f8808m18(暂无匿称)

    好文章.学习了.

    0