GUT:胰腺囊肿的人群发病率及是否有害你知道么?

2017-09-10 MedSci MedSci原创

近期,发表在杂志GUT上的一项基于人群的纵向研究评估了偶然性发现的胰腺囊肿的患病率、发病率和临床相关性。此项研究共招募了2333名来自波美拉尼亚人口健康研究(SHIP)的参与者,其中有1077名参与者(521名男性,平均年龄55.8±12.8岁)在基线研究时(2008-2012年)进行了磁共振胰胆管造影(MRCP)。MRCP进行了直径≥2mm的胰腺囊肿的分析。在1077名受试者中有676名受试者接

近期,发表在杂志GUT上的一项基于人群的纵向研究评估了偶然性发现的胰腺囊肿的患病率、发病率和临床相关性。


此项研究共招募了2333名来自波美拉尼亚人口健康研究(SHIP)的参与者,其中有1077名参与者(521名男性,平均年龄55.8±12.8岁)在基线研究时(2008-2012年)进行了磁共振胰胆管造影(MRCP)。MRCP进行了直径≥2mm的胰腺囊肿的分析。在1077名受试者中有676名受试者接受了为期5年的随访(2014-2016年)。根据年龄、性别和疑似流行病学风险因素评估了胰腺囊肿的发生率和发生率(加权参与研究)。所有SHIP参与者在2015年进行了死亡随访(平均随访期5.9年,范围3.2-7.5年)。

此项研究结果显示:在基线时,胰腺囊肿的加权患病率为49.1%,平均数量为3.9个囊肿(95%CI 3.2至4.5)。囊肿大小范围从2毫米到29毫米。患病率(p <0.001)、数量(p = 0.001)和最大大小(p <0.001)随着年龄增长显着。5年随访发现,新发胰腺囊肿的加权发生率为12.9%。最初含有胰腺囊肿的受试者中57.1%显示出囊肿数量和/或囊肿大小的增加。在接受MRCP的所有受试者中,在随访期间没有参与者死于胰腺疾病。

此项研究表明:人群中胰腺囊肿的患病率较高,其数量和大小随年龄增长而增加。总体而言,在5年随访期间,该人群中未观察到胰腺癌的发生。然而,前瞻性随访成像显示出超过50%的进展。只有约6%的囊肿和2.5%的受试人群最初发现超过1厘米的囊肿。

原始出处:
Kromrey ML, Bülow R, et al. Prospective study on the incidence, prevalence and 5-year pancreatic-related mortality of pancreatic cysts in a population-based study. Gut. 2017 Sep 6. pii: gutjnl-2016-313127. doi: 10.1136/gutjnl-2016-313127.  

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    2017-09-18 戒馋,懒,贪

    谢谢分享.学习了

    0

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    2017-09-12 ylzr123

    好文.值得点赞!认真学习了.把经验应用于实践.为患者解除病痛.

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1823377, encodeId=2d8118233e784, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Mon Mar 19 01:45:00 CST 2018, time=2018-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=245294, encodeId=ba6f24529436, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Mon Sep 18 09:49:46 CST 2017, time=2017-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=243132, encodeId=0ad6243132bb, content=好文.值得点赞!认真学习了.把经验应用于实践.为患者解除病痛., beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Sep 12 08:28:45 CST 2017, time=2017-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1340755, encodeId=9c2e1340e5544, content=<a href='/topic/show?id=74a140404de' target=_blank style='color:#2F92EE;'>#囊肿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40404, encryptionId=74a140404de, topicName=囊肿)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=32a12500167, createdName=12498ca5m83暂无昵称, createdTime=Tue Sep 12 03:45:00 CST 2017, time=2017-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1604500, encodeId=600a160450030, content=<a href='/topic/show?id=6caf83951ab' target=_blank style='color:#2F92EE;'>#胰腺囊肿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83951, encryptionId=6caf83951ab, topicName=胰腺囊肿)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0e8d19200231, createdName=wenzhiren, createdTime=Tue Sep 12 03:45:00 CST 2017, time=2017-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242609, encodeId=2fda24260959, content=学习啦!谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Sun Sep 10 20:32:50 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242580, encodeId=4d0d24258025, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sun Sep 10 18:32:39 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242568, encodeId=4e6224256895, content=学习了.涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Sun Sep 10 17:05:10 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242538, encodeId=1ce82425387b, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sun Sep 10 13:42:32 CST 2017, time=2017-09-10, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1823377, encodeId=2d8118233e784, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Mon Mar 19 01:45:00 CST 2018, time=2018-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=245294, encodeId=ba6f24529436, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Mon Sep 18 09:49:46 CST 2017, time=2017-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=243132, encodeId=0ad6243132bb, content=好文.值得点赞!认真学习了.把经验应用于实践.为患者解除病痛., beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Sep 12 08:28:45 CST 2017, time=2017-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1340755, encodeId=9c2e1340e5544, content=<a href='/topic/show?id=74a140404de' target=_blank style='color:#2F92EE;'>#囊肿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40404, encryptionId=74a140404de, topicName=囊肿)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=32a12500167, createdName=12498ca5m83暂无昵称, createdTime=Tue Sep 12 03:45:00 CST 2017, time=2017-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1604500, encodeId=600a160450030, content=<a href='/topic/show?id=6caf83951ab' target=_blank style='color:#2F92EE;'>#胰腺囊肿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83951, encryptionId=6caf83951ab, topicName=胰腺囊肿)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0e8d19200231, createdName=wenzhiren, createdTime=Tue Sep 12 03:45:00 CST 2017, time=2017-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242609, encodeId=2fda24260959, content=学习啦!谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Sun Sep 10 20:32:50 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242580, encodeId=4d0d24258025, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sun Sep 10 18:32:39 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242568, encodeId=4e6224256895, content=学习了.涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Sun Sep 10 17:05:10 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242538, encodeId=1ce82425387b, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sun Sep 10 13:42:32 CST 2017, time=2017-09-10, status=1, ipAttribution=)]
    2017-09-10 tanxingdoctor

    学习啦!谢谢分享!

    0

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    2017-09-10 清风拂面

    谢谢分享.学习了

    0

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    2017-09-10 王秀

    学习了.涨知识了!

    0

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    2017-09-10 131****1460

    学习了受益匪浅

    0

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