CMAJ:结肠憩室炎新疗法

2012-09-14 不详 网络

    最近,发表在加拿大医学会杂志《CMAJ》上的一篇综述总结了结肠憩室炎的最新证据和可能有助于临床医师管理和治疗该病的新疗法。     憩室疾病(在结肠壁形成的囊样突出)在发达国家很常见,但是该病在全球正在增多,原因可能是生活方式的改变。在该病患者中,约25%的人将出现症状,包括腹痛和排便习惯改变,往往会使医师作出肠易激综合征的诊断

    最近,发表在加拿大医学会杂志《CMAJ》上的一篇综述总结了结肠憩室炎的最新证据和可能有助于临床医师管理和治疗该病的新疗法。

    憩室疾病(在结肠壁形成的囊样突出)在发达国家很常见,但是该病在全球正在增多,原因可能是生活方式的改变。在该病患者中,约25%的人将出现症状,包括腹痛和排便习惯改变,往往会使医师作出肠易激综合征的诊断。结肠镜的广泛应用使更多“无并发症的”憩室炎得到诊断,即“有憩室炎症的体征,但没有结肠穿孔、脓肿或其他并发症”。

    最新的证据表明,憩室炎急性发作复发的的一个危险因素。最近初步研究表明,美沙拉嗪在预防憩室炎复发方面显着优于安慰剂。然而,这些结果仅以摘要形式发表。益生菌也显示出治疗该病的前景,但是目前还缺少高质量的证据。

    “憩室疾病的病理生理学极其复杂,因为该病有多种致病因素,包括饮食、结肠壁的结构、肠运动和可能的遗传易感性。” Antonio Tursi博士说,“随着最近我们对这种复杂疾病的了解的进展,治疗憩室炎的新疗法可能会进一步改变临床实践。
       

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1391430, encodeId=1e55139143090, content=<a href='/topic/show?id=b5be53e91fc' target=_blank style='color:#2F92EE;'>#憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53791, encryptionId=b5be53e91fc, topicName=憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sun Sep 16 06:20:00 CST 2012, time=2012-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522701, encodeId=03891522e0180, content=<a href='/topic/show?id=14d853e8918' target=_blank style='color:#2F92EE;'>#憩室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53789, encryptionId=14d853e8918, topicName=憩室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=33b211483971, createdName=zutt, createdTime=Sun Sep 16 06:20:00 CST 2012, time=2012-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1523799, encodeId=f8cf1523e997c, content=<a href='/topic/show?id=7170e87563e' target=_blank style='color:#2F92EE;'>#结肠憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78756, encryptionId=7170e87563e, topicName=结肠憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4e5311558208, createdName=guojianrong, createdTime=Sun Sep 16 06:20:00 CST 2012, time=2012-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554412, encodeId=05f215544120f, content=<a href='/topic/show?id=74e458559f5' target=_blank style='color:#2F92EE;'>#新疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58559, encryptionId=74e458559f5, topicName=新疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d03114536414, createdName=kcb074, createdTime=Sun Sep 16 06:20:00 CST 2012, time=2012-09-16, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1391430, encodeId=1e55139143090, content=<a href='/topic/show?id=b5be53e91fc' target=_blank style='color:#2F92EE;'>#憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53791, encryptionId=b5be53e91fc, topicName=憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sun Sep 16 06:20:00 CST 2012, time=2012-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522701, encodeId=03891522e0180, content=<a href='/topic/show?id=14d853e8918' target=_blank style='color:#2F92EE;'>#憩室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53789, encryptionId=14d853e8918, topicName=憩室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=33b211483971, createdName=zutt, createdTime=Sun Sep 16 06:20:00 CST 2012, time=2012-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1523799, encodeId=f8cf1523e997c, content=<a href='/topic/show?id=7170e87563e' target=_blank style='color:#2F92EE;'>#结肠憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78756, encryptionId=7170e87563e, topicName=结肠憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4e5311558208, createdName=guojianrong, createdTime=Sun Sep 16 06:20:00 CST 2012, time=2012-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554412, encodeId=05f215544120f, content=<a href='/topic/show?id=74e458559f5' target=_blank style='color:#2F92EE;'>#新疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58559, encryptionId=74e458559f5, topicName=新疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d03114536414, createdName=kcb074, createdTime=Sun Sep 16 06:20:00 CST 2012, time=2012-09-16, status=1, ipAttribution=)]
    2012-09-16 zutt
  3. [GetPortalCommentsPageByObjectIdResponse(id=1391430, encodeId=1e55139143090, content=<a href='/topic/show?id=b5be53e91fc' target=_blank style='color:#2F92EE;'>#憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53791, encryptionId=b5be53e91fc, topicName=憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sun Sep 16 06:20:00 CST 2012, time=2012-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522701, encodeId=03891522e0180, content=<a href='/topic/show?id=14d853e8918' target=_blank style='color:#2F92EE;'>#憩室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53789, encryptionId=14d853e8918, topicName=憩室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=33b211483971, createdName=zutt, createdTime=Sun Sep 16 06:20:00 CST 2012, time=2012-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1523799, encodeId=f8cf1523e997c, content=<a href='/topic/show?id=7170e87563e' target=_blank style='color:#2F92EE;'>#结肠憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78756, encryptionId=7170e87563e, topicName=结肠憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4e5311558208, createdName=guojianrong, createdTime=Sun Sep 16 06:20:00 CST 2012, time=2012-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554412, encodeId=05f215544120f, content=<a href='/topic/show?id=74e458559f5' target=_blank style='color:#2F92EE;'>#新疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58559, encryptionId=74e458559f5, topicName=新疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d03114536414, createdName=kcb074, createdTime=Sun Sep 16 06:20:00 CST 2012, time=2012-09-16, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1391430, encodeId=1e55139143090, content=<a href='/topic/show?id=b5be53e91fc' target=_blank style='color:#2F92EE;'>#憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53791, encryptionId=b5be53e91fc, topicName=憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sun Sep 16 06:20:00 CST 2012, time=2012-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522701, encodeId=03891522e0180, content=<a href='/topic/show?id=14d853e8918' target=_blank style='color:#2F92EE;'>#憩室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53789, encryptionId=14d853e8918, topicName=憩室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=33b211483971, createdName=zutt, createdTime=Sun Sep 16 06:20:00 CST 2012, time=2012-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1523799, encodeId=f8cf1523e997c, content=<a href='/topic/show?id=7170e87563e' target=_blank style='color:#2F92EE;'>#结肠憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78756, encryptionId=7170e87563e, topicName=结肠憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4e5311558208, createdName=guojianrong, createdTime=Sun Sep 16 06:20:00 CST 2012, time=2012-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554412, encodeId=05f215544120f, content=<a href='/topic/show?id=74e458559f5' target=_blank style='color:#2F92EE;'>#新疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58559, encryptionId=74e458559f5, topicName=新疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d03114536414, createdName=kcb074, createdTime=Sun Sep 16 06:20:00 CST 2012, time=2012-09-16, status=1, ipAttribution=)]
    2012-09-16 kcb074