JACC:收缩压变异性越大,危害就越大

2016-09-21 MedSci MedSci原创

人体内血压(BP)会随着时间而动态波动。以往的研究表明更大的收缩压(SBP)变异性与不良结果呈负相关性。然而,这些研究都有显著的限制性,例如样本数量小,人群的选择,以及限制性的结果。来自美国的研究人员开展了一项研究,这项研究在一项大型美国退伍军人队列研究中,探讨了随访变异性增加和全因死亡率,心血管事件和终末期肾病(ESRD)的关系。在2005年和2006年期间,在3285684名美国退伍军人中(有

人体内血压(BP)会随着时间而动态波动。以往的研究表明更大的收缩压(SBP)变异性与不良结果呈负相关性。然而,这些研究都有显著的限制性,例如样本数量小,人群的选择,以及限制性的结果。来自美国的研究人员开展了一项研究,这项研究在一项大型美国退伍军人队列研究中,探讨了随访变异性增加和全因死亡率,心血管事件和终末期肾病(ESRD)的关系。在2005年和2006年期间,在3285684名美国退伍军人中(有和没有高血压及正常估计肾小球滤过率(EGFR)),研究人员确定了2865157例有8次或更多门诊血压测量的患者。每个人的收缩压变异性(SBPV)通过使用所有SBP值(正态分布)的SD进行测量。SD四分位数(<10.3,10.3至12.7,12.7至15.6,以及≥15.6 mmHg)与全因死亡率,冠心病事件(CHD),卒中,以及ESRD有关,该联系性使用Cox模型确定,该模型对社会人口学特征,基线eGFR,合并症,身体质量指数,收缩压,舒张压,和抗高血压药物的使用进行了调整。一些社会人口变量(年龄,男性,非洲裔种族,离婚或丧偶状态)和临床特征(较低的基线eGFR,更高的收缩压和舒张压),

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    2017-01-09 hbwxf
  2. 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  3. 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createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Thu Sep 22 16:08:00 CST 2016, time=2016-09-22, status=1, ipAttribution=)]
    2016-09-25 doctorJiangchao

    继续关注

    0

  4. 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createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Thu Sep 22 16:08:00 CST 2016, time=2016-09-22, status=1, ipAttribution=)]
    2016-09-25 doctorJiangchao

    继续学习

    0

  5. 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    2016-09-23 187清风

    血压的重要性

    0

  6. 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    2016-09-23 187清风

    继续学习

    0

  7. 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    2016-09-23 187清风

    厉害,学习了

    0

  8. 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  9. 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  10. 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createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Thu Sep 22 16:08:00 CST 2016, time=2016-09-22, status=1, ipAttribution=)]
    2016-09-22 jyzxjiangqin

    危害大的变异性越大。

    0