Diabetic Med:中国成人2型糖尿病患者体重指数与死亡风险?

2018-12-25 MedSci MedSci原创

近日,国际杂志 《Diabetic Med》上在线发表一项关于中国成人2型糖尿病患者体重指数与死亡风险的研究。研究人员通过检查BMI与2型糖尿病患者的全因,心血管疾病(CVD)特异性和癌症特异性死亡风险之间的关系,从而为人群中的体重管理提供建议。 这项回顾性队列研究于2004年1月1日至2014年12月31日期间在中国上海的52 763名新诊断为2型糖尿病的人中进行。通过与上海人口动态统计

近日,国际杂志 《Diabetic Med》上在线发表一项关于中国成人2糖尿病患者体重指数与死亡风险的研究。研究人员通过检查BMI2糖尿病患者的全因,血管疾病(CVD)特异性和癌症特异性死亡风险之间的关系,从而为人群中的体重管理提供建议。

这项回顾性队列研究于200411日至20141231日期间在中国上海的52 763名新诊断2糖尿病的人中进行。通过与上海人口动态统计数据相关联,确定了所有死亡病例。分析中包括大约52 488人。使用Kaplan-Meier方法绘制具有不同BMI类别的人的存活曲线。Cox比例风险模型来分别检查BMI与死亡风险之间的潜在非线性或线性关系。

在平均6年的随访期间共发现4777例死亡。在男性的BMI和全因死亡率之间观察到L形关联(P为总体关联<0.001P为非线性<0.001),而在女性中发现U形关联(P为总体关联<0.001P表示非线性<0.001)。在男性中,BMI与癌症特异性和CVD特异性死亡率无显著相关性。在女性中,随着BMI的增加,癌症特异性死亡的风险增加,而BMI的降低与CVD特异性死亡率的增加有关。

BMI较低的男性和BMI较低或高的女性全因死亡率增加表明中国成人2型糖尿病患者的BMI保持在正常范围内的重要性。

原始出处:

H. XuM. ZhangD. Xuet al. Body mass index and the risk of mortality among Chinese adults with Type 2 diabetes

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content=好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Dec 25 12:16:22 CST 2018, time=2018-12-25, status=1, ipAttribution=)]
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content=好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Dec 25 12:16:22 CST 2018, time=2018-12-25, status=1, ipAttribution=)]
  9. 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content=好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Dec 25 12:16:22 CST 2018, time=2018-12-25, status=1, ipAttribution=)]
    2018-12-25 misszhang

    谢谢MedSci提供最新的资讯

    0

  10. 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content=好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Dec 25 12:16:22 CST 2018, time=2018-12-25, status=1, ipAttribution=)]
    2018-12-25 ylzr123

    好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。

    0

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Hypertension:高血压对于长期高体重指数和动脉硬化之间的介导效应

肥胖和高血压是动脉硬化的重要危险因素,然而,体重指数(BMI)增加,血压升高(BP)和动脉硬化的复杂关系在很大程度上尚未可知。Yang Liu等研究者发表于Hypertension的一项研究,目的是探讨升高的BP对中年人早期BMI、BMI长期增加及其与动脉硬化趋势关系的介导作用。

J Periodontal Res: 唾液乳酸脱氢酶水平与全身炎症的关系

据报道,唾液乳酸脱氢酶(LDH)是筛选牙周病的有用参数。我们进行了一项横断面研究,以验证唾液LDH作为牙周炎生物标志物的有效性,并通过测量唾液LDH和血清高敏C-反应蛋白(hs-CRP)水平来研究牙周炎严重程度与全身炎症的关系。