JAHA:育龄女性妊娠和非妊娠期首次卒中风险有何差异?

2017-04-22 xing.T MedSci原创

虽然在育龄妇女首次卒中的绝对风险较低,医疗保健专业人员应注意到妊娠和产后早期卒中的相对风险大大增加。

妊娠妇女与相似年龄的非妊娠妇女相比,其卒中风险可能有所增加,但这种风险的大小和时机尚不清楚。近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员旨在探究育龄妇女首次卒中事件的风险,并比较了妊娠期间和产后早期的卒中风险与这些时期以外的基础卒中风险。

研究人员使用链接的初级(临床实践研究数据链)和次级(医院统计)英国护理记录,在1997年4月1日至2014年3月31日期间年龄为15至49岁的2046048名女性中进行了一项开放的队列研究。首次卒中的风险是通过计算产前、围生期(分娩前2天到后1天)、产后早期(产后前6周)和晚期(产后第二个6周)脑卒中发病率来进行评估,并与非妊娠期进行比较。研究人员使用了泊松回归模型,并对产妇年龄、社会经济团体和日历时间进行了调整。

共有2511名女性发生首次卒中,非妊娠期女性脑卒中的发病率为25人每100000人每年(95%可信区间为24-26)。产前卒中发生率较低(10.7人每100000人每年,95%可信区间为7.6-15.1),但围产期增加了9倍(161.1人每100000人每年,95%可信区间为80.6-322.1),产后早期升高3倍(47.1人每100000人每年,95%可信区间为31.3-70.9)。缺血性和出血性脑卒中发生率在围产期及产后早期均有所增加。

虽然在育龄妇女首次卒中的绝对风险较低,医疗保健专业人员应注意到妊娠和产后早期卒中的相对风险大大增加。

原始出处:

Lu Ban,et al. Incidence of First Stroke in Pregnant and Nonpregnant Women of Childbearing Age: A Population‐Based Cohort Study From England.JAHA.2017. https://doi.org/10.1161/JAHA.116.004601

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    2017-04-26 大爰

    分析的透彻学习了!!

    0

  3. 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    2017-04-25 ylzr123

    好文,值得点赞,更值得收藏!慢慢领会学习的。给点个赞!

    0

  4. 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    2017-04-24 baihao215

    大数据的处理带来的多是管理决策,学习了

    0

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createdTime=Sun Apr 23 10:01:42 CST 2017, time=2017-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=189809, encodeId=f09d18980997, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=74221626377, createdName=tofsw, createdTime=Sun Apr 23 07:48:49 CST 2017, time=2017-04-23, status=1, ipAttribution=)]
    2017-04-24 zhaohui6731
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  8. 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time=2017-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=189914, encodeId=531c18991483, content=非常好的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Sun Apr 23 14:13:53 CST 2017, time=2017-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=189850, encodeId=51c918985028, content=学习知识了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Sun Apr 23 10:01:42 CST 2017, time=2017-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=189809, encodeId=f09d18980997, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=74221626377, createdName=tofsw, createdTime=Sun Apr 23 07:48:49 CST 2017, time=2017-04-23, status=1, ipAttribution=)]
    2017-04-23 天涯183

    非常好的文章,学习了

    0

  9. 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createdTime=Sun Apr 23 10:01:42 CST 2017, time=2017-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=189809, encodeId=f09d18980997, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=74221626377, createdName=tofsw, createdTime=Sun Apr 23 07:48:49 CST 2017, time=2017-04-23, status=1, ipAttribution=)]
    2017-04-23 flysky120

    学习知识了,谢谢

    0

  10. 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time=2017-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=189914, encodeId=531c18991483, content=非常好的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Sun Apr 23 14:13:53 CST 2017, time=2017-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=189850, encodeId=51c918985028, content=学习知识了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Sun Apr 23 10:01:42 CST 2017, time=2017-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=189809, encodeId=f09d18980997, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=74221626377, createdName=tofsw, createdTime=Sun Apr 23 07:48:49 CST 2017, time=2017-04-23, status=1, ipAttribution=)]
    2017-04-23 tofsw

    学习了谢谢分享

    0

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左旋甲状腺素可由胃肠道吸收,但吸收不完全,吸收率不定,特别是在与食物同服时。2017年3月,发表在《N Engl J Med》的研究对怀孕期间被认定为患有亚临床甲状腺功能减退症或低甲状腺素血症的妇女使用左旋甲状腺素治疗是否会改善其孩子的认知功能进行了实验分析。背景:怀孕期间亚临床甲状腺疾病可能与不良结局有关,包括后代智商低于正常水平。在怀孕期间被认定为患有亚临床甲状腺功能减退症或低甲状腺素血症的妇

Obstet Gynecol:计划性妊娠与孕妇酒精摄入之间有啥关系?

大多数妇女,无论有无计划性,在意识到妊娠后会停止或减少饮酒。这表明早点知道妊娠的意识可能比在所有妊娠的女性中提倡戒酒要更有效。

Obstet Gynecol:既往进行减肥手术的妇女妊娠时腹部手术的风险如何?

由此可见,减肥手术与妊娠期间腹部手术的风险增加相关。

Hypertension:妊娠的易卒中自发性高血压大鼠尿中多肽组学有啥变化?

该研究首次强调了尿调节素的潜在作用以及它在高血压妊娠中的聚合。

Am J Reprod Immunol:阿司匹林和低分子肝素通过改变滋养层功能改善病态妊娠

阿司匹林和低分子肝素通过改变滋养层功能改善病态妊娠。