JAHA:先天性矫正型大动脉转位患者三尖瓣手术的长期预后

2018-03-18 xiangting MedSci原创

先天性矫正型大动脉转位患者进行三尖瓣手术治疗可获得满意的远期预后。

对于先天性矫正型大动脉转位患者,通常认为瓣膜成形术是不成功的。三尖瓣手术的最佳时机对于这些患者至关重要。

研究人员回顾性分析了57例接受三尖瓣手术的先天性矫正型大动脉转位患者。11例接受三尖瓣成形术,46例接受三尖瓣置换术。三尖瓣成形术组平均随访时间为7.4±5.5年,三尖瓣置换术组平均随访时间为5.6±3.6年(p= 0.33)。对于所有的57例患者,1年,5年和10年的生存率或无移植率分别为96.4%,91.6%和75.6%。随访期间大多数(90%)患者的右心室射血分数仍然保留(≥40%)。在一组高选择性三尖瓣成形术患者中,虽然长期生存率和右心室功能与三尖瓣置换相似,但60%的患者出现三尖瓣反流。多变量Cox回归分析发现术前右心室舒张末期内径(每增加1厘米;危险比3.22; p= 0.02)是术后死亡率或需要移植的独立预测因子。右室舒张末期内径≥60mm的手术患者与右室舒张末内径<60 mm的患者相比,生存率显著降低(p = 0.003)。

先天性矫正型大动脉转位患者进行三尖瓣手术治疗可获得满意的远期预后。接受三尖瓣成形术的患者经常出现三尖瓣反流。术前右室舒张末期内径是晚期死亡率的危险因素,应在心脏扩大和功能障碍之前进行手术以获得最佳预后。

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    2018-03-20 zhaohui6731
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    2018-03-20 huirong
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  6. [GetPortalCommentsPageByObjectIdResponse(id=2068799, encodeId=b7ce2068e9964, content=<a href='/topic/show?id=61111963600' target=_blank style='color:#2F92EE;'>#三尖瓣手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19636, encryptionId=61111963600, topicName=三尖瓣手术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Fri Jun 22 23:58:00 CST 2018, time=2018-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1645590, encodeId=f414164559080, content=<a href='/topic/show?id=79d99e04630' target=_blank style='color:#2F92EE;'>#长期预后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97046, encryptionId=79d99e04630, topicName=长期预后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0e4823226485, createdName=ymljack, createdTime=Thu May 24 14:58:00 CST 2018, time=2018-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267773, encodeId=0196126e773de, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Tue Mar 20 05:58:00 CST 2018, time=2018-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369353, encodeId=fe331369353f2, content=<a href='/topic/show?id=bc9f28589d0' target=_blank style='color:#2F92EE;'>#先天性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28589, encryptionId=bc9f28589d0, topicName=先天性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a435298, createdName=huirong, createdTime=Tue Mar 20 05:58:00 CST 2018, time=2018-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1578456, encodeId=de8315e8456e3, content=<a href='/topic/show?id=a1021962883' target=_blank style='color:#2F92EE;'>#三尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19628, encryptionId=a1021962883, topicName=三尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7cb16409801, createdName=124985dbm11(暂无昵称), createdTime=Tue Mar 20 05:58:00 CST 2018, time=2018-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=297433, encodeId=c5f529e43303, content=好文章.学习了., beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sun Mar 18 15:29:50 CST 2018, time=2018-03-18, status=1, ipAttribution=)]
    2018-03-18 1e0f8808m18(暂无匿称)

    好文章.学习了.

    0