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JASN：维持性血液透析患者住院存在性别差异！

2017-04-29 xing.T MedSci原创

血液透析住院性别差异
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这些研究结果表明，接受维持性血液透析的妇女住院和30天再入院的风险明显高于男性。在这个队列中，在年龄最小的患者中性别差异最大，并且考虑血清白蛋白水平反映的健康状况的不同后，住院的性别差异有所减弱。

住院是维持血液透析的终末期肾脏病（ESRD）患者发生疾病的主要原因，也是患者医疗保健费用增加一个重要贡献因素。

近日，肾脏病领域权威杂志Journal of the American Society of Nephrology上发表一篇研究文章，为了确定住院最高风险的亚组，研究人员分析了性别、年龄、种族各个层次的住院率，调整了人口统计学和临床特征；并且分析了333756名住院患者的30天再住院率，其中111653名住院患者在美国（2007-2011年期间）的一个大型透析组织中接受维持性血液透析。

研究人员发现总体住院率为每人每年住院1.85次，并且女性住院率比男性高高（女性与男性相比，每年住院率为2.08人 vs. 1.68人，P＜0.001）。同一种族特定年龄组住院率均有女性比男性要高，而在年轻的患者中差异最大（例如，18-34岁的女性和≥75岁的女性比相应的男性住院率要分别高出54% [95%可信区间为42%-67%]和14%[95%可信区间为11%-18%]）。女性患者也有较高的30天再入院风险，在年轻患者中差异最大。女性的血清白蛋白水平明显低于男性，而通过血清白蛋白水平的分层后，年龄组特异性住院率和30天再住院率的性别差异有所减弱。

这些研究结果表明，接受维持性血液透析的妇女住院和30天再入院的风险明显高于男性。在这个队列中，在年龄最小的患者中性别差异最大，并且考虑血清白蛋白水平反映的健康状况的不同后，住院的性别差异有所减弱。

原始出处：

Scott V. Adams,et al. Sex Differences in Hospitalizations with Maintenance Hemodialysis. JASN, 2017,http://jasn.asnjournals.org/content/early/2017/04/20/ASN.2016090986.abstract

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    2017-05-18 chenhongpeng

    #ASN#

    0

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    2017-05-04 zhangqingzui

    每天看一看，加深加深印象

    0

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time=2017-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=192341, encodeId=8ecd19234175, content=学习了感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuNreCBwuEU9I5ich0uE1zdHnicdKjEibG64cgLHSp5sMMFMiatLiaDaSrGOj1jAaDuTZo7vDLDhgRFHt6/0, createdBy=caa52003923, createdName=狼毒花1982, createdTime=Mon May 01 04:57:19 CST 2017, time=2017-05-01, status=1, ipAttribution=)]
    2017-05-03 zhangqingzui

    学习了，感谢，慢慢消化

    0

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time=2017-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=192341, encodeId=8ecd19234175, content=学习了感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuNreCBwuEU9I5ich0uE1zdHnicdKjEibG64cgLHSp5sMMFMiatLiaDaSrGOj1jAaDuTZo7vDLDhgRFHt6/0, createdBy=caa52003923, createdName=狼毒花1982, createdTime=Mon May 01 04:57:19 CST 2017, time=2017-05-01, status=1, ipAttribution=)]
    2017-05-03 童小孩

    学习

    0

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time=2017-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=192341, encodeId=8ecd19234175, content=学习了感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuNreCBwuEU9I5ich0uE1zdHnicdKjEibG64cgLHSp5sMMFMiatLiaDaSrGOj1jAaDuTZo7vDLDhgRFHt6/0, createdBy=caa52003923, createdName=狼毒花1982, createdTime=Mon May 01 04:57:19 CST 2017, time=2017-05-01, status=1, ipAttribution=)]
    2017-05-02 童小孩

    学习

    0

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    2017-05-01 ewsr6

    #透析患者#

    0

  7. 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createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K3j7ibEWPiarwpqibEYqqX9yVibV5uebib0O7hQSOPmqGrb5FfyDbLsLawnz7ShAb5ibtiayWgI5ClMTh5v/0, createdBy=a47c1614293, createdName=童小孩, createdTime=Wed May 03 08:44:11 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=192786, encodeId=a286192e86c1, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K3j7ibEWPiarwpqibEYqqX9yVibV5uebib0O7hQSOPmqGrb5FfyDbLsLawnz7ShAb5ibtiayWgI5ClMTh5v/0, createdBy=a47c1614293, createdName=童小孩, createdTime=Tue May 02 08:55:42 CST 2017, time=2017-05-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1570607, encodeId=287215e0607bd, content=<a href='/topic/show?id=e53d94835a5' target=_blank style='color:#2F92EE;'>#透析患者#</a>, 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encodeId=e2c819244041, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K3j7ibEWPiarwpqibEYqqX9yVibV5uebib0O7hQSOPmqGrb5FfyDbLsLawnz7ShAb5ibtiayWgI5ClMTh5v/0, createdBy=a47c1614293, createdName=童小孩, createdTime=Mon May 01 08:28:58 CST 2017, time=2017-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=192367, encodeId=9bf519236ea4, content=好多是国外文献，适合中国人吗？, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuBA90ng5ibXMmibn1feGOQ2cjw0S48DKsF0icicFlmRxwHibIic2TNGd22vVqkKRMj2cRSWbpqZAPBPgdt/0, createdBy=81031668757, createdName=林3301, createdTime=Mon May 01 07:07:19 CST 2017, time=2017-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=192341, encodeId=8ecd19234175, content=学习了感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuNreCBwuEU9I5ich0uE1zdHnicdKjEibG64cgLHSp5sMMFMiatLiaDaSrGOj1jAaDuTZo7vDLDhgRFHt6/0, createdBy=caa52003923, createdName=狼毒花1982, createdTime=Mon May 01 04:57:19 CST 2017, time=2017-05-01, status=1, ipAttribution=)]
    2017-05-01 habb

    #血液透析#

    0

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time=2017-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=192341, encodeId=8ecd19234175, content=学习了感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuNreCBwuEU9I5ich0uE1zdHnicdKjEibG64cgLHSp5sMMFMiatLiaDaSrGOj1jAaDuTZo7vDLDhgRFHt6/0, createdBy=caa52003923, createdName=狼毒花1982, createdTime=Mon May 01 04:57:19 CST 2017, time=2017-05-01, status=1, ipAttribution=)]
    2017-05-01 童小孩

    学习

    0

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time=2017-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=192341, encodeId=8ecd19234175, content=学习了感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuNreCBwuEU9I5ich0uE1zdHnicdKjEibG64cgLHSp5sMMFMiatLiaDaSrGOj1jAaDuTZo7vDLDhgRFHt6/0, createdBy=caa52003923, createdName=狼毒花1982, createdTime=Mon May 01 04:57:19 CST 2017, time=2017-05-01, status=1, ipAttribution=)]
    2017-05-01 林3301

    好多是国外文献，适合中国人吗？

    0

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    2017-05-01 狼毒花1982

    学习了感谢分享

    0

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