Chest:运动训练和CPAP对心力衰竭和OSA患者的影响

2018-09-12 xing.T MedSci原创

由此可见,在HF和OSA患者中,该研究的初步结果显示单独的运动可以改善OSA,提高生活质量,但CPAP不能。在HF患者OSA的治疗中,该研究是唯一的一项显示任何治疗(运动)可改善所有研究参数的随机试验。该研究的结果突出了运动的重要治疗益处,特别是对于CPAP依从性较低的个体。

运动和CPAP可改善OSA。近日,呼吸领域权威杂志chest上发表了一篇研究文章,该研究评估了运动对心力衰竭(HF)和OSA患者的影响。

HF和OSA患者被随机分配到以下研究组:对照组、运动组、CPAP组和运动+CPAP组。

65名参与者完成了研究方案。研究人员将治疗后3个月的指标与基线进行了比较,平均呼吸暂停-低通气指数(AHI)与对照组没有显著变化(每小时事件发生率),运动组适度降低(28±17 vs. 18±12; P<0.03),CPAP组(32±25 vs. 8±11; P<0.007)和运动+CPAP组(25±1 vs. 10±16; P<0.007)显著降低。只有运动组峰耗氧量峰值、肌肉力量和耐力才有所改善。运动和CPAP都改善了受试者的主观过度白天嗜睡、生活质量和纽约心功能分级。然而,与对照组相比,36项医疗结局研究简表调查和明尼苏达生活心力衰竭问卷调查的分数变化仅在运动组中显著改善。

由此可见,在HF和OSA患者中,该研究的初步结果显示单独的运动可以改善OSA,提高生活质量,但CPAP不能。在HF患者OSA的治疗中,该研究是唯一的一项显示任何治疗(运动)可改善所有研究参数的随机试验。该研究的结果突出了运动的重要治疗益处,特别是对于CPAP依从性较低的个体。

原始出处:


Denise Maria Servantes,et al.Effects of Exercise Training and CPAP in Patients With Heart Failure and OSA.chest.2018.https://doi.org/10.1016/j.chest.2018.05.011

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    2019-08-19 Smile2680
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