Neurology:普通人群反复创伤性脑损伤流行病学调查!

2017-10-26 xing.T MedSci原创

rTBI是一般人群TBI负担的一个重要因素。一些危险因素可以有助于识别这些反复受伤的高危人群。然而,需要高质量的研究来改善rTBI的监测手段。

近日,神经病学领域权威取杂志Neurology上发表了一篇研究文章,研究人员旨在全面评估一般人群中反复性脑外伤(rTBI)的风险与危险因素。

研究人员系统地检索了MEDLINE、EMBASE数据库,并将截止至2017年1月16日发表的报道了一般人群rTBI风险或危险因素的观察性研究纳入分析。由于研究之间存在方法学的异质性,估计并不是通过Meta分析,而是采用了Meta回归分析。

二十二项研究报告了复发风险,十一项研究报告了27个潜在的危险因素。rTBI风险具有异质性,变化范围从0.43%(95%可信区间为0.19%-0.67%)到41.92%(95%可信区间为34.43%-49.40%),随着随访时间(3天-55年)而变化。复发的中位时间为0.5-3.8年。在从多个护理点确定病例的研究中,至少有5.50%(95%可信区间为4.80%-6.30%)的患者在随访1年后出现复发。使用行政数据/自我报告调查确定病例的研究倾向于报告更高的风险。在不止一个研究中报道的与rTBI显著相关的TBI危险因素包括男性、既往TBI、中度或重度TBI和酒精中毒。在单个研究中与rTBI显著相关的TBI危险因素包括癫痫、不寻求医疗保健治疗和表明社会经济地位较低的多个因素。

由此可见,rTBI是一般人群TBI负担的一个重要因素。一些危险因素可以有助于识别这些反复受伤的高危人群。然而,需要高质量的研究来改善rTBI的监测手段。

原始出处:

Oliver Lasry,et al. Epidemiology of recurrent traumatic brain injury in the general population A systematic review.Neurology. 2017. http://www.neurology.org/content/early/2017/10/25/WNL.0000000000004671.abstract

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content=<a href='/topic/show?id=abfd6539566' target=_blank style='color:#2F92EE;'>#流行病学调查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65395, encryptionId=abfd6539566, topicName=流行病学调查)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bc93846316, createdName=charl1234568, createdTime=Sat Oct 28 04:02:00 CST 2017, time=2017-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1614763, encodeId=52d01614e638c, content=<a href='/topic/show?id=b77f59959f2' target=_blank style='color:#2F92EE;'>#普通人群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59959, encryptionId=b77f59959f2, topicName=普通人群)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1b9519540847, createdName=ms9476844295372110, createdTime=Sat Oct 28 04:02:00 CST 2017, time=2017-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256127, encodeId=727225612eab, content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Oct 26 13:16:52 CST 2017, time=2017-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256117, encodeId=ebc625611e70, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Thu Oct 26 13:08:06 CST 2017, time=2017-10-26, status=1, ipAttribution=)]
  5. 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createdName=amyloid, createdTime=Sat Jan 06 17:02:00 CST 2018, time=2018-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1335180, encodeId=87211335180e9, content=<a href='/topic/show?id=e7cc32022c7' target=_blank style='color:#2F92EE;'>#创伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32022, encryptionId=e7cc32022c7, topicName=创伤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aa5a2500103, createdName=ms920641618706883, createdTime=Sat Oct 28 04:02:00 CST 2017, time=2017-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1397357, encodeId=d6aa139e357b7, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, 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content=<a href='/topic/show?id=abfd6539566' target=_blank style='color:#2F92EE;'>#流行病学调查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65395, encryptionId=abfd6539566, topicName=流行病学调查)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bc93846316, createdName=charl1234568, createdTime=Sat Oct 28 04:02:00 CST 2017, time=2017-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1614763, encodeId=52d01614e638c, content=<a href='/topic/show?id=b77f59959f2' target=_blank style='color:#2F92EE;'>#普通人群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59959, encryptionId=b77f59959f2, topicName=普通人群)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1b9519540847, createdName=ms9476844295372110, createdTime=Sat Oct 28 04:02:00 CST 2017, time=2017-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256127, encodeId=727225612eab, content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Oct 26 13:16:52 CST 2017, time=2017-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256117, encodeId=ebc625611e70, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Thu Oct 26 13:08:06 CST 2017, time=2017-10-26, status=1, ipAttribution=)]
    2017-10-28 xugumin
  6. 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content=<a href='/topic/show?id=abfd6539566' target=_blank style='color:#2F92EE;'>#流行病学调查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65395, encryptionId=abfd6539566, topicName=流行病学调查)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bc93846316, createdName=charl1234568, createdTime=Sat Oct 28 04:02:00 CST 2017, time=2017-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1614763, encodeId=52d01614e638c, content=<a href='/topic/show?id=b77f59959f2' target=_blank style='color:#2F92EE;'>#普通人群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59959, encryptionId=b77f59959f2, topicName=普通人群)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1b9519540847, createdName=ms9476844295372110, createdTime=Sat Oct 28 04:02:00 CST 2017, time=2017-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256127, encodeId=727225612eab, content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Oct 26 13:16:52 CST 2017, time=2017-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256117, encodeId=ebc625611e70, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, 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  7. 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content=<a href='/topic/show?id=abfd6539566' target=_blank style='color:#2F92EE;'>#流行病学调查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65395, encryptionId=abfd6539566, topicName=流行病学调查)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bc93846316, createdName=charl1234568, createdTime=Sat Oct 28 04:02:00 CST 2017, time=2017-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1614763, encodeId=52d01614e638c, content=<a href='/topic/show?id=b77f59959f2' target=_blank style='color:#2F92EE;'>#普通人群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59959, encryptionId=b77f59959f2, topicName=普通人群)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1b9519540847, createdName=ms9476844295372110, createdTime=Sat Oct 28 04:02:00 CST 2017, time=2017-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256127, encodeId=727225612eab, content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Oct 26 13:16:52 CST 2017, time=2017-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256117, encodeId=ebc625611e70, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Thu Oct 26 13:08:06 CST 2017, time=2017-10-26, status=1, ipAttribution=)]
  8. 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04:02:00 CST 2017, time=2017-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256127, encodeId=727225612eab, content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Oct 26 13:16:52 CST 2017, time=2017-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256117, encodeId=ebc625611e70, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Thu Oct 26 13:08:06 CST 2017, time=2017-10-26, status=1, ipAttribution=)]
    2017-10-26 惠映实验室

    学习了.谢谢.

    0

  9. 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04:02:00 CST 2017, time=2017-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256127, encodeId=727225612eab, content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Oct 26 13:16:52 CST 2017, time=2017-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256117, encodeId=ebc625611e70, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Thu Oct 26 13:08:06 CST 2017, time=2017-10-26, status=1, ipAttribution=)]
    2017-10-26 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0